Ethyl 3-chloro-2-ethoxy-6-fluorobenzoate CAS 2387253-96-3
| CAS No. | 2387253-96-3 |
| Molecular Formula | C11H12ClFO3 |
| Molecular Weight | 246.66 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Compared with other compounds in its class, the molecular weight of 246.66 g/mol gives Ethyl 3-chloro-2-ethoxy-6-fluorobenzoate distinctive chromatographic separation conditions and mass-spectrometry parameter settings.
Ethyl 3-chloro-2-ethoxy-6-fluorobenzoate (CAS 2387253-96-3) is a high-purity analytical reference standard with the molecular formula C11H12ClFO3 and a molecular weight of 246.66 g/mol.
The molecular framework of Ethyl 3-chloro-2-ethoxy-6-fluorobenzoate (C11H12ClFO3) is characterized by a carboxylic acid group, a hydroxyl group, an ether linkage, fluorine/chlorine substitution, an aromatic ring system. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
CATO manufactures Ethyl 3-chloro-2-ethoxy-6-fluorobenzoate under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C11H12ClFO3 |
| Molecular Weight | 246.66 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, ethanol, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 5.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1999 |
| Halogen Content | F/Cl-containing |
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Recommended Standards
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- Methyl 3-chloro-5-fluoro-4-isopropoxybenzoate (CAS 2432848-72-9)
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- 4-(3-Bromophenyl)-6-methylpyrimidin-2-amine (CAS 913322-49-3)
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- 3-(4-Acetyl-3,5-dimethyl-1h-pyrazol-1-yl)propanoic acid (CAS 890596-67-5)
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