2-(4-Chloro-8-iodo-7-methylpyrazolo[1,5-a][1,3,5]triazin-2-yl)propan-2-ol CAS 2387601-68-3
| CAS No. | 2387601-68-3 |
| Molecular Formula | C9H10ClIN4O |
| Molecular Weight | 352.56 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including 2-(4-Chloro-8-iodo-7-methylpyrazolo[1,5-a][1,3,5]triazin-2-yl)propan-2-ol.
2-(4-Chloro-8-iodo-7-methylpyrazolo[1,5-a][1,3,5]triazin-2-yl)propan-2-ol (CAS 2387601-68-3), molecular formula C9H10ClIN4O and molecular weight 352.56 g/mol, is a CATO reference standard with documented purity and traceability.
The molecular framework of 2-(4-Chloro-8-iodo-7-methylpyrazolo[1,5-a][1,3,5]triazin-2-yl)propan-2-ol (C9H10ClIN4O) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, chlorine/iodine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C9H10ClIN4O |
| Molecular Weight | 352.56 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 6.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1999 |
| Halogen Content | Cl/I-containing |
| Nitrogen Atoms | 4 |
Related Chloro Standards
- 8-Chloro-2-(2,4-dichlorophenyl)quinoline-4-carboxylic acid (CAS 863180-69-2)
- 8-Chloro-2-(2,5-dichlorophenyl)quinoline-4-carboxylic acid (CAS 863180-70-5)
- 8-Chloro-2-(3,4-dichlorophenyl)quinoline-4-carboxylic acid (CAS 863180-68-1)
- (R)-6-Chloro-1-(1-(2,4-dichlorophenyl)ethyl)-1H-pyrazolo[3,4-b]pyrazine-3-carbonitrile (CAS 2174940-60-2)
- 2-Chloro-2-(4'-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenylhydrazono)acetic acid ethyl ester (CAS 1310384-14-5)
- 2-(3-Chloro-5-(methoxymethoxy)-2-((1S,2R)-2-methylcyclopropyl)phenyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane (CAS 2758756-24-8)
- rel-2-(3-Chloro-5-(methoxymethoxy)-2-((1R,2S)-2-methylcyclopropyl)phenyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane (CAS 2791273-52-2)
- Ethyl 3-(2-chloro-6-fluoro-4-(trifluoromethyl)phenoxy)-1H-pyrazole-5-carboxylate (CAS 1338333-96-2)
Recommended Standards
- 3,3',5,5'-Tetraisopropyl-[1,1'-biphenyl]-4,4'-diamine (CAS 186703-54-8)
- 4,4'-Diheptyl-2,2'-bipyridine (CAS 71071-44-8)
- Octadecylsuccinic anhydride (CAS 47458-32-2)
- N-(tert-Butyldimethylsilyl)-3-fluoro-5-(2-hydroxypropan-2-yl)thiophene-2-sulfonimidamide (CAS 2271371-29-8)
- 5-((4-Chlorobenzyl)thio)-1-methyl-3-(trifluoromethyl)-1H-pyrazole-4-carbaldehyde (CAS 321553-32-6)
- 2-Cyclopropylimidazo[1,2-a]pyridine-6-carboxylic acid (CAS 1343134-57-5)
- 2-(4-(Difluoromethyl)-2-fluoro-5-hydroxypyridin-3-yl)acetic acid (CAS 1806923-38-5)
- 6-(N-Methyl-3,4-xylidino)uracil (CAS 36995-89-8)
- Tenofovir Impurity 75 (CAS 30566-31-5)
- Chiglitazar Sodium Impurity Ⅰ-1 (CAS 56080-28-5)
- 2-Methoxycycloheptan-1-amine hydrochloride (CAS 1375474-17-1)
- PCN-222(Zr） (CAS 1403461-06-2)
- 7-Methyl-3,6,9,12-tetraoxatetradecane (CAS 67715-79-1)
- Semaglutide impurity 67 (CAS CATO-C4X-222667)
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