4-Chloro-8-iodo-7-methylpyrazolo[1,5-a][1,3,5]triazine-2-carboxylic acid CAS 2387601-71-8
| CAS No. | 2387601-71-8 |
| Molecular Formula | C7H4ClIN4O2 |
| Molecular Weight | 338.49 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Compared with other compounds in its class, the molecular weight of 338.49 g/mol gives 4-Chloro-8-iodo-7-methylpyrazolo[1,5-a][1,3,5]triazine-2-carboxylic acid distinctive chromatographic separation conditions and mass-spectrometry parameter settings.
4-Chloro-8-iodo-7-methylpyrazolo[1,5-a][1,3,5]triazine-2-carboxylic acid (CAS 2387601-71-8), molecular formula C7H4ClIN4O2 and molecular weight 338.49 g/mol, is a CATO reference standard with documented purity and traceability.
4-Chloro-8-iodo-7-methylpyrazolo[1,5-a][1,3,5]triazine-2-carboxylic acid (C7H4ClIN4O2) contains an amide group, a carboxylic acid group, a hydroxyl group, an ether linkage, chlorine/iodine substitution, an aromatic ring system. It is notably hygroscopic, halogen substitution raises its density and boiling point, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
As a certified reference material (CRM), 4-Chloro-8-iodo-7-methylpyrazolo[1,5-a][1,3,5]triazine-2-carboxylic acid meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C7H4ClIN4O2 |
| Molecular Weight | 338.49 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 7.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1999 |
| Halogen Content | Cl/I-containing |
| Nitrogen Atoms | 4 |
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- 1-{[(E)-(5-Chloro-3-iodo-2-methylphenyl)diazenyl]oxy}ethanone (CAS 1260388-68-8)
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Recommended Standards
- 4,4-Dipentylazoxybenzene (CAS 37592-87-3)
- 7-((Dicyclohexylamino)methyl)quinolin-8-ol (CAS 82280-18-0)
- 4-(Diisopropylamino)-2,2-diphenylbutyramide (CAS 39666-27-8)
- Adamantan-1-yl(4-benzylpiperazin-1-yl)methanone (CAS 31879-79-5)
- 3-Amino-3-(4-fluorophenyl)propanamide hydrochloride (CAS 1159812-52-8)
- 5-Chloro-1,7-naphthyridine (CAS 67967-10-6)
- (Butan-2-yl)[(3-methoxyphenyl)methyl]amine (CAS 889949-80-8)
- 2-Chloro-3,4-difluorobenzoic Acid (CAS 150444-93-2)
- 7-Aminoheptanoic acid (CAS 929-17-9)
- 3-Methoxy-N-(4-(methoxymethyl)-6-methyl-2-oxo-1,2-dihydroquinolin-7-yl)benzamide (CAS 866050-76-2)
- tert-Butyl 3-((3-methoxyquinoxalin-2-yl)amino)piperidine-1-carboxylate (CAS 1065485-08-6)
- 4-Methoxy-2-methyl-1-methylsulfanylbenzene (CAS 22583-04-6)
- 4-(4-Chlorophenyl)-5-(methylsulfonyl)-2-thioxo-1,2-dihydropyridine-3-carbonitrile (CAS 1447960-52-2)
- Insulin Degludec Impurity 3 (CAS CATO-C4X-21573)
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