5-Fluoro-2-(trifluoromethyl)phenylacetic acid CAS 239135-52-5
| CAS No. | 239135-52-5 |
| Molecular Formula | C9H6F4O2 |
| Molecular Weight | 222.14 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including 5-Fluoro-2-(trifluoromethyl)phenylacetic acid.
5-Fluoro-2-(trifluoromethyl)phenylacetic acid (CAS 239135-52-5), molecular formula C9H6F4O2 and molecular weight 222.14 g/mol, is a CATO reference standard with documented purity and traceability.
5-Fluoro-2-(trifluoromethyl)phenylacetic acid (C9H6F4O2) contains a carboxylic acid group, a hydroxyl group, an ether linkage, fluorine substitution, an aromatic ring system. Halogen substitution raises its density and boiling point, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
CATO manufactures 5-Fluoro-2-(trifluoromethyl)phenylacetic acid under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C9H6F4O2 |
| Molecular Weight | 222.14 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at room temperature, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 5.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | F-containing |
Related Fluoro Standards
- 1-(4-Fluoro-3-(trifluoromethyl)phenyl)urea (CAS 1000588-77-1)
- 3-fluoro-2-methyl-4-(trifluoromethyl)benzoic acid (CAS 1070761-76-0)
- 2-Fluoro-5-(trifluoromethyl)benzohydrazide (CAS 1079843-54-1)
- 1-(3-Fluoro-4-(trifluoromethoxy)phenyl)ethan-1-one (CAS 1174006-08-6)
- 2-Fluoro-5-methyl-4-(trifluoromethyl)benzoic acid (CAS 1323955-61-8)
- 2-Fluoro-3-methoxy-4-(trifluoromethyl)benzaldehyde (CAS 1352719-37-9)
- 1-(3-Fluoro-5-(trifluoromethoxy)phenyl)ethan-1-one (CAS 1352999-53-1)
- 4-Fluoro-3-methyl-5-(trifluoromethyl)benzoic acid (CAS 1373920-63-8)
Recommended Standards
- 5-bromo-2-(trideuteriomethyl)indazole (CAS 2447686-91-9)
- 6-Fluoro-2-methyl-3-(trifluoromethyl)benzoic acid (CAS 2384761-72-0)
- 4-Fluoro-N’-hydroxy-2-(trifluoromethyl)benzimidamide (CAS 934607-28-0)
- 6-Fluoro-3-methyl-2-(trifluoromethyl)benzoic acid (CAS 2383927-14-6)
- 5-(Ethylsulfonyl)-4-(m-tolyl)-1,2,3-thiadiazole (CAS 1708259-48-6)
- ARP, 95% (CAS 627090-10-2)
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- 3-(2,4,5-Trimethylphenyl)prop-2-en-1-amine (CAS 1344804-22-3)
- 3-(3,4-Dichlorophenyl)prop-2-yn-1-amine (CAS 1183904-53-1)
- 5-(2-Isobutyl)-4-amino-1H-pyrazole-3-carboxylic acid (CAS 1093415-88-3)
- 3-Chloro-5-methoxy-1H-pyrrolo[2,3-b]pyridine (CAS 1190317-59-9)
- 5-Chloro-2-methylphenylmagnesium bromide, 0.50 M in THF (CAS 1393737-19-3)
- 3,14,16-Trihydroxycard-20(22)-enolide (CAS 1537179-45-5)
- Liraglutide Impurity 18 TFA Salt (CAS CATO-C4X-199218)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com