4-(2-Hydroxyethyl)piperazin-2-one CAS 23936-04-1

Purity 97%+In StockPharmaceutical Standards
CAS No.23936-04-1
Molecular FormulaC6H12N2O2
Molecular Weight144.17 g/mol
CategoryPharmaceutical Standards / API Standards
AvailabilityIn Stock

Chemical Structure

4-(2-Hydroxyethyl)piperazin-2-one CAS 23936-04-1 chemical structure

Description

4-(2-Hydroxyethyl)piperazin-2-one (CAS 23936-04-1), molecular formula C6H12N2O2 and molecular weight 144.17 g/mol, is a CATO reference standard with documented purity and traceability.

The molecular framework of 4-(2-Hydroxyethyl)piperazin-2-one (C6H12N2O2) is characterized by an amino-acid-derived structure, an amide group, a hydroxyl group, an ether linkage. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.

Physical & Chemical Properties

Molecular FormulaC6H12N2O2
Molecular Weight144.17 g/mol
Purity97%+
StorageStore at 2-8°C, protect from light, keep sealed and dry
Solubility (reference)Soluble in DMSO, DMF, methanol
StabilityLight-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening
Degree of Unsaturation (DBE)2.0
CAS Registry Year (est.)1963
Nitrogen Atoms2

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