4-Chloroisoquinoline-1-carbonitrile CAS 23994-20-9
| CAS No. | 23994-20-9 |
| Molecular Formula | C10H5ClN2 |
| Molecular Weight | 188.61 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Structurally, 4-Chloroisoquinoline-1-carbonitrile (C10H5ClN2) contains a nitrogen-containing heterocyclic scaffold, a nitrile group, chlorine substitution. The molecule exhibits a degree of unsaturation (DBE) of 9.0, corresponding to approximately 9 ring(s) or double-bond equivalent(s). With a molecular weight of 188.61 g/mol, it falls into the medium-molecular-weight range. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
4-Chloroisoquinoline-1-carbonitrile (CAS 23994-20-9), molecular formula C10H5ClN2 and molecular weight 188.61 g/mol, is a CATO reference standard with documented purity and traceability.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
As a certified reference material (CRM), 4-Chloroisoquinoline-1-carbonitrile meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C10H5ClN2 |
| Molecular Weight | 188.61 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, faint amine-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 9.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1963 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 2 |
Related Chloroisoquinoline Standards
- 1-Chloroisoquinoline-5-carbonitrile (CAS 1231761-23-1)
- 1-Chloroisoquinoline-8-carbonitrile (CAS 1231761-24-2)
- 5-Chloroisoquinoline-1-carbonitrile (CAS 1231761-25-3)
- 8-Chloroisoquinoline-1-carbonitrile (CAS 1231761-26-4)
- 4-Chloroisoquinoline-5-carbonitrile (CAS 1231761-27-5)
- 3-Chloroisoquinoline-1-carbonitrile (CAS 1237431-75-2)
- 5-Chloroisoquinoline-8-carbonitrile (CAS 1256463-60-1)
- 8-Chloroisoquinoline-5-carbonitrile (CAS 1256463-61-2)
Recommended Standards
- 4-Chloro-6-cyanoquinoline (CAS 219763-83-4)
- 4-Chloro-N-(4H-1,2,4-triazol-3-yl)butanamide (CAS 901347-49-7)
- 4-Chloro-5-hydroxy-2-propylpyridazin-3(2H)-one (CAS 64178-61-6)
- 4-Chloroquinoline-2-carbonitrile (CAS 4552-43-6)
- n-(Piperidin-3-ylmethyl)acetamide (CAS 90346-06-8)
- Ethyl 1-ethyl-5-oxo-4,5-dihydro-1h-pyrazole-3-carboxylate (CAS 1315368-17-2)
- N-allyl-4-methyl-2-phenylthiazole-5-carboxamide (CAS 320420-85-7)
- 3,6-Dibromo-9-(4-(tert-butyl)phenyl)-9H-carbazole (CAS 741293-42-5)
- Bilastine Impurity 74 (CAS CATO-C4X-225374)
- Methyl 6-methyl-2-oxo-1,2-dihydropyridine-3-carboxylate (CAS 51146-06-6)
- 6-Chloro-[3,3'-bipyridine]-5-carbonitrile (CAS 1214346-69-6)
- 6-hydroxypyridazine-3-carboxylic acid (CAS 37972-69-3)
- 1-Methyl-3-(3-(triethoxysilyl)propyl)-1H-imidazol-3-ium chloride (CAS 338741-79-0)
- Semaglutide Sodium Salt (CAS CATO-C4X-222620)
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