5-Phenyl-1,3,4-thiadiazol-2(3H)-one CAS 24028-40-8

Description

Compared with other compounds in its class, the molecular weight of 178.21 g/mol gives 5-Phenyl-1,3,4-thiadiazol-2(3H)-one distinctive chromatographic separation conditions and mass-spectrometry parameter settings.

5-Phenyl-1,3,4-thiadiazol-2(3H)-one (CAS 24028-40-8) is a high-purity analytical reference standard with the molecular formula C8H6N2OS and a molecular weight of 178.21 g/mol.

The molecular framework of 5-Phenyl-1,3,4-thiadiazol-2(3H)-one (C8H6N2OS) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, sulfur-containing functionality, a hydroxyl group, an ether linkage. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).

Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.

The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.

Physical & Chemical Properties

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