2-(4-Nitrophenyl)-1,3-dioxolane CAS 2403-53-4
| CAS No. | 2403-53-4 |
| Molecular Formula | C9H9NO4 |
| Molecular Weight | 195.17 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including 2-(4-Nitrophenyl)-1,3-dioxolane.
2-(4-Nitrophenyl)-1,3-dioxolane (CAS 2403-53-4), molecular formula C9H9NO4 and molecular weight 195.17 g/mol, is a CATO reference standard with documented purity and traceability.
2-(4-Nitrophenyl)-1,3-dioxolane (C9H9NO4) contains an amino-acid-derived structure, an amide group, a hydroxyl group, an ether linkage. It is notably hygroscopic, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
As a certified reference material (CRM), 2-(4-Nitrophenyl)-1,3-dioxolane meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C9H9NO4 |
| Molecular Weight | 195.17 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (faint amine-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in methanol, ethanol, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 6.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1957 |
| Nitrogen Atoms | 1 |
Related Nitrophenyl Standards
- 2-(3-Methyl-5-nitrophenyl)acetic acid (CAS 1261444-79-4)
- (R)-2-(4-nitrophenyl)propanoic acid (CAS 142927-07-9)
- (S)-2-(4-nitrophenyl)propanoic acid (CAS 142927-08-0)
- 2-(3-Methyl-4-nitrophenyl)acetic Acid (CAS 143665-37-6)
- 3-(3-Nitrophenyl)propionic Acid (CAS 1664-57-9)
- 3-(4-Nitrophenyl)propionic Acid (CAS 16642-79-8)
- 4-Nitrophenyl propionate (CAS 1956-06-5)
- 2-(2-Methyl-5-nitrophenyl)acetic acid (CAS 287119-83-9)
Recommended Standards
- 2-(4-Methyl-2-nitrophenyl)acetic acid (CAS 29640-90-2)
- 2-(5-Methyl-2-nitrophenyl)acetic Acid (CAS 37777-81-4)
- 2-(3-Nitrophenyl)propanoic acid (CAS 21762-10-7)
- 2-(6-Formyl-4-methoxypyridin-2-yl)acetic acid (CAS 681234-50-4)
- 2,5-Dichloro-3-methoxypyrazine (CAS 36398-43-3)
- 3-(4-Bromo-2-methylphenyl)propanoic acid (CAS 24078-17-9)
- 4-Iodobenzoyl cyanide (CAS 198978-33-5)
- N-(2-iodophenyl)-3,4-dihydro-2H-pyrrol-5-amine (CAS 745028-14-2)
- Fmoc-D-Pra-OH (CAS 220497-98-3)
- 5-Isopropyl-3-(methoxycarbonyl)-2H-cyclohepta[b]furan-2-one (CAS 99909-62-3)
- 1-[(3-fluorophenyl)methyl]-1h-1,2,4-triazol-3-amine (CAS 832740-71-3)
- 5-(3-Chlorophenyl)-4-methylisoxazole-3-carbonyl chloride (CAS 88958-16-1)
- 6-(4-methoxyphenyl)-3H,4H-thieno[3,2-d]pyrimidin-4-one (CAS 225385-22-8)
- Des-Gln19-Tirzepatide (CAS CATO-CPTD788954)
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