3-(4-(Trifluoromethyl)phenyl)piperidin-3-ol hydrochloride CAS 2409589-75-7
| CAS No. | 2409589-75-7 |
| Molecular Formula | C12H14F3NO |
| Molecular Weight | N/A |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
3-(4-(Trifluoromethyl)phenyl)piperidin-3-ol hydrochloride (CAS 2409589-75-7) is a high-purity analytical reference standard with the molecular formula C12H14F3NOHCl and a molecular weight of 281.70 g/mol.
The molecular framework of 3-(4-(Trifluoromethyl)phenyl)piperidin-3-ol hydrochloride (C12H14F3NOHCl) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine/chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
As a certified reference material (CRM), 3-(4-(Trifluoromethyl)phenyl)piperidin-3-ol hydrochloride meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C12H14F3NO HCl |
| Molecular Weight | 281.70 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 4.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2000 |
| Halogen Content | F/Cl-containing |
| Nitrogen Atoms | 1 |
Related Trifluoromethyl Standards
- 3-(4-(Trifluoromethyl)phenyl)pyrrolidin-3-ol hydrochloride (CAS 1000198-74-2)
- 3-(4-(Trifluoromethyl)phenyl)pyrrolidine (CAS 1000198-76-4)
- (2-Methyl-4-(trifluoromethyl)thiazol-5-yl)methanol (CAS 1000339-72-9)
- methyl 3-((4-(trifluoromethyl)piperidin-1-yl)methyl)benzoate (CAS 1000339-86-5)
- methyl 4-(2-(4-(trifluoromethyl)piperidin-1-yl)ethoxy)benzoate (CAS 1000339-87-6)
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- 3-(2-(4-(trifluoromethyl)piperidin-1-yl)ethyl)benzaldehyde (CAS 1000339-89-8)
- 4-(2-(4-(trifluoromethyl)piperidin-1-yl)acetyl)-1H-pyrrole-2-carbaldehyde (CAS 1000339-90-1)
Recommended Standards
- 1-((1-(Cyclopropylsulfonyl)piperidin-4-yl)methyl)-3-phenylurea (CAS 1235618-66-2)
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- 2-Chlorophenyl (3-methylbenzofuran-2-yl)carbamate (CAS 61307-33-3)
- (4-((Triisopropylsilyl)oxy)phenyl)methanol (CAS 611182-95-7)
- 2-((4-Methylpiperazin-1-yl)methyl)-5,6,7,8-tetrahydrobenzo[4,5]thieno[2,3-d]pyrimidin-4(1H)-one (CAS 20886-99-1)
- 8-Chloro-5-fluoro-3-methoxy-1,7-naphthyridine (CAS 1600511-84-9)
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- 7-Bromo-2,3,4,5-tetrahydro-1H-benzo[c]azepine hydrochloride (CAS 2007908-53-2)
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