5-([1,1'-Biphenyl]-4-yl)-2-(trifluoromethyl)furan-3-carboxylic acid CAS 241154-06-3
| CAS No. | 241154-06-3 |
| Molecular Formula | C18H11F3O3 |
| Molecular Weight | 332.27 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including 5-([1,1'-Biphenyl]-4-yl)-2-(trifluoromethyl)furan-3-carboxylic acid.
CATO supplies 5-([1,1'-Biphenyl]-4-yl)-2-(trifluoromethyl)furan-3-carboxylic acid (CAS 241154-06-3), a certified reference material (molecular formula C18H11F3O3, MW 332.27 g/mol) for analytical method development and quality control.
The molecular framework of 5-([1,1'-Biphenyl]-4-yl)-2-(trifluoromethyl)furan-3-carboxylic acid (C18H11F3O3) is characterized by a steroid core, a hydroxyl group, an ether linkage, fluorine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
As a certified reference material (CRM), 5-([1,1'-Biphenyl]-4-yl)-2-(trifluoromethyl)furan-3-carboxylic acid meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C18H11F3O3 |
| Molecular Weight | 332.27 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 12.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | F-containing |
Related Biphenyl Standards
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- 1-([1,1'-Biphenyl]-4-ylmethyl)-3-(4,6-dimethylpyrimidin-2-yl)guanidine (CAS 685896-77-9)
- 2-([1,1'-Biphenyl]-4-yloxy)-N-(3,4-dimethylphenyl)acetamide (CAS 300673-76-1)
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Recommended Standards
- 3-{[(2,6-dichlorophenyl)methyl]sulfanyl}-N-methylthiophene-2-carboxamide (CAS 251097-34-4)
- C2-Bis-phosphoramidic acid diethyl ester (CAS 34008-16-7)
- 3-((2,4-Dichlorobenzyl)thio)-N-methylthiophene-2-carboxamide (CAS 303151-44-2)
- Chlorambucil ethyl ester (CAS 64977-24-8)
- 3-{[(2-chloro-6-fluorophenyl)methyl]sulfanyl}-5-[(E)-2-[(4-chlorophenyl)amino]ethenyl]-1,2-thiazole-4-carbonitrile (CAS 338778-77-1)
- (3-(5-Bromopyridin-3-yl)isoxazol-5-yl)methanol (CAS 1231244-47-5)
- N-Butyl-4-methyl-N-(4-methyloxazol-2-yl)benzamide (CAS 57067-88-6)
- rel-((1R,2S,5S)-6,6-Dimethyl-3-azabicyclo[3.1.0]hexan-2-yl)methanol (CAS 540787-92-6)
- 8,9-Dimethyl-9H-purine-6-carboxylic acid (CAS 1095823-07-6)
- 2-((4-Allyl-5-(thiophen-2-yl)-4H-1,2,4-triazol-3-yl)thio)-N-(4-(benzyloxy)phenyl)acetamide (CAS 573705-89-2)
- (1H-inden-3-yl)boronic acid (CAS 1356166-66-9)
- a-CGRP (29-37) (canine, mouse, rat) (H-5746.0001) (CAS 219991-19-2)
- 2-{[(6,7-dimethoxy-4-oxo-3,4-dihydroquinazolin-2-yl)methyl]sulfanyl}acetic acid (CAS 1010916-57-0)
- Fragment-[3-31]-Semaglutide (CAS CATO-C4X-2226113)
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