tert-butyl 6-iodo-2-azaspiro[3.4]octane-2-carboxylate CAS 2411635-57-7
| CAS No. | 2411635-57-7 |
| Molecular Formula | C12H20INO2 |
| Molecular Weight | 337.20 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
tert-butyl 6-iodo-2-azaspiro[3.4]octane-2-carboxylate (CAS 2411635-57-7), molecular formula C12H20INO2 and molecular weight 337.20 g/mol, is a CATO reference standard with documented purity and traceability.
The molecular framework of tert-butyl 6-iodo-2-azaspiro[3.4]octane-2-carboxylate (C12H20INO2) is characterized by an amide group, a carboxylic acid group, a hydroxyl group, an ether linkage, iodine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
CATO manufactures tert-butyl 6-iodo-2-azaspiro[3.4]octane-2-carboxylate under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C12H20INO2 |
| Molecular Weight | 337.20 g/mol |
| Appearance | White to pale yellow crystalline powder. (slight halide-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 3.0 |
| UV Absorption | UV-absorbing |
| CAS Registry Year (est.) | 2000 |
| Halogen Content | I-containing |
| Nitrogen Atoms | 1 |
Recommended Standards
- tert-butyl 3-iodo-8-azabicyclo[3.2.1]octane-8-carboxylate (CAS 2674113-13-2)
- tert-Butyl 8-iodo-3-azabicyclo[3.2.1]octane-3-carboxylate (CAS 2820191-20-4)
- tert-Butyl 2-iodo-6-azaspiro[3.4]octane-6-carboxylate (CAS 2681279-36-5)
- tert-butyl exo-3-iodo-8-azabicyclo[3.2.1]octane-8-carboxylate (CAS 2750168-72-8)
- Ethyl imidazo[2,1-b][1,3,4]thiadiazole-6-carboxylate (CAS 96356-04-6)
- (S)-2-((1H-benzo[d]imidazol-4-yl)oxy)propanoic acid (CAS 2068138-05-4)
- N-(4-(Ethyl(2-hydroxyethyl)amino)cyclohexyl)acetamide (CAS 1353985-15-5)
- 2-(Pyrazin-2-yloxy)benzonitrile (CAS 1221723-55-2)
- (4-Chloro-2-methylphenyl)(3-methoxyphenyl)methanone (CAS 775329-34-5)
- Ethyl 2-(3-Bromophenyl)-2,2-difluoroacetate (CAS 885068-75-7)
- 6-(Methylsulfonyl)-2,6-diazaspiro[3.5]nonane (CAS 2138283-12-0)
- 8-tert-Butyl-4-(2,4,6-trimethylbenzoyl)-1-oxa-4-azaspiro[4.5]decane-3-carboxylic acid (CAS 1326808-52-9)
- (7-Fluorochroman-2-yl)methanol (CAS 1193393-01-9)
- Semaglutide impurity 46 (CAS CATO-C4X-222646)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com