tert-butyl 3-(cyanomethyl)-3-(hydroxymethyl)azetidine-1-carboxylate CAS 2413097-50-2
| CAS No. | 2413097-50-2 |
| Molecular Formula | C11H18N2O3 |
| Molecular Weight | 226.27 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
tert-butyl 3-(cyanomethyl)-3-(hydroxymethyl)azetidine-1-carboxylate (CAS 2413097-50-2), molecular formula C11H18N2O3 and molecular weight 226.27 g/mol, is a CATO reference standard with documented purity and traceability.
The molecular framework of tert-butyl 3-(cyanomethyl)-3-(hydroxymethyl)azetidine-1-carboxylate (C11H18N2O3) is characterized by an amino-acid-derived structure, an amide group, a hydroxyl group, an ether linkage. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
As a certified reference material (CRM), tert-butyl 3-(cyanomethyl)-3-(hydroxymethyl)azetidine-1-carboxylate meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C11H18N2O3 |
| Molecular Weight | 226.27 g/mol |
| Appearance | Off-white to pale yellow crystalline powder |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in methanol, ethanol, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 4.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2000 |
| Nitrogen Atoms | 2 |
Recommended Standards
- tert-butyl 2-oxo-3,8-diazabicyclo[3.2.1]octane-8-carboxylate (CAS 417727-40-3)
- Tert-butyl 3-(cyanomethyl)morpholine-4-carboxylate (CAS 886365-51-1)
- Tert-butyl (S)-2-(cyanomethyl)morpholine-4-carboxylate (CAS 2091029-57-9)
- Tert-butyl 3-oxo-2,5-diazabicyclo[5.1.0]Octane-5-carboxylate (CAS 2368895-01-4)
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