Oseltamivir impurity 276 CAS 2413185-98-3
| CAS No. | 2413185-98-3 |
| Molecular Formula | C20H35NO5 |
| Molecular Weight | 369.50 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Oseltamivir impurity 276 (CAS 2413185-98-3) is a certified pharmaceutical impurity reference standard with the molecular formula C20H35NO5 and a molecular weight of 369.50 g/mol.
Structurally, Oseltamivir impurity 276 (C20H35NO5) contains a steroid core, an amide group, a hydroxyl group, an ether linkage. The molecule exhibits a degree of unsaturation (DBE) of 4.0, corresponding to approximately 4 ring(s) or double-bond equivalent(s). With a molecular weight of 369.50 g/mol, it falls into the moderately-high-molecular-weight range. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C20H35NO5 |
| Molecular Weight | 369.50 g/mol |
| Appearance | Off-white to pale yellow crystalline powder |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 4.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2000 |
| Nitrogen Atoms | 1 |
Related Oseltamivir Standards
- Oseltamivir Impurity 127 (CAS CATO-C4X-1720127)
- Oseltamivir impurity 277 (CAS CATO-C4X-1720277)
- Oseltamivir Impurity 284 (CAS CATO-C4X-1720284)
- Oseltamivir Impurity 98 (CAS CATO-C4X-172098)
- Oseltamivir Impurity 100 (CAS CATO-C4X-1720100)
- Oseltamivir impurity 204 (CAS CATO-C4X-1720204)
- Oseltamivir Impurity 245 (CAS 2765792-93-4)
- Oseltamivir Impurity 257 (CAS CATO-C4X-1720257)
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