4'-Bromospiro[adamantane-2,9'-fluorene] CAS 2415337-01-6
| CAS No. | 2415337-01-6 |
| Molecular Formula | C22H21Br |
| Molecular Weight | 365.31 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The molecular framework of 4'-Bromospiro[adamantane-2,9'-fluorene] (C22H21Br) is characterized by bromine substitution, a polycyclic aromatic system. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
4'-Bromospiro[adamantane-2,9'-fluorene] (CAS 2415337-01-6) is a high-purity analytical reference standard with the molecular formula C22H21Br and a molecular weight of 365.31 g/mol.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
As a certified reference material (CRM), 4'-Bromospiro[adamantane-2,9'-fluorene] meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C22H21Br |
| Molecular Weight | 365.31 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 12.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2000 |
| Halogen Content | Br-containing |
Related Bromospiro Standards
- 1'-Benzyl-6-bromospiro[indoline-3,4'-piperidin]-2-one (CAS 1258638-01-5)
- 1'-Benzyl-6-bromospiro[chroman-2,4'-piperidin]-4-one (CAS 81109-72-0)
- 2'-Bromospiro[[1,3]dithiolane-2,9'-fluorene] (CAS 113425-37-9)
- 1’-Boc-6-bromospiro[chroman-2,4’-piperidin]-4-one (CAS 690632-38-3)
- Benzyl 5-bromospiro[indole-3,4'-piperidine]-1'-carboxylate (CAS 1375076-92-8)
- 7-Bromospiro[chromane-2,3'-thietan]-4-one 1',1'-dioxide (CAS 2200003-26-3)
- 1'-Acetyl-6-bromospiro[indoline-3,4'-piperidin]-2-one (CAS 1160248-50-9)
- 6'-Bromospiro[cyclobutane-1,2'-thiochroman]-4'-one 1',1'-dioxide (CAS 2198098-45-0)
Recommended Standards
- 2-[6-(3-methoxyphenyl)-3-methyl-4-(trifluoromethyl)-1h-pyrazolo[3,4-b]pyridin-1-yl]acetic acid (CAS 937605-92-0)
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- 2-[6-(2-methoxyphenyl)-3-methyl-4-(trifluoromethyl)-1h-pyrazolo[3,4-b]pyridin-1-yl]acetic acid (CAS 937605-90-8)
- 6,7-Dimethoxy-N-[4-(trifluoromethoxy)phenyl]quinazolin-4-amine (CAS 296234-68-9)
- (Methoxycarbonyl)-L-alanine (CAS 59190-99-7)
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- 7-(Trifluoromethyl)-7,8-dihydroquinazolin-5(6H)-one (CAS 1420794-79-1)
- 1,3-Dimethyl-6-(1-methylhydrazinyl)pyrimidine-2,4(1H,3H)-dione (CAS 4318-53-0)
- 4-Fluorothioanisole D4 (CAS 1189510-57-3)
- (R)-3-((((9H-fluoren-9-yl)methoxy)carbonyl)amino)-4,4,4-trifluorobutanoic acid (CAS 1310680-34-2)
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- Dimethyloxaloylglycine (CAS 89464-63-1)
- 2,4-Dichloropyrimidine-5-carbaldehyde (CAS 871254-61-4)
- D-Phe22-Tirzepatide (CAS CATO-CPTD788912)
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