(2-Chloro-4-ethoxy-3-fluorophenyl)boronic acid CAS 2415657-87-1

Purity 97%+In StockPharmaceutical Standards
CAS No.2415657-87-1
Molecular FormulaC8H9BClFO3
Molecular Weight218.42 g/mol
CategoryPharmaceutical Standards / API Standards
AvailabilityIn Stock

Chemical Structure

(2-Chloro-4-ethoxy-3-fluorophenyl)boronic acid CAS 2415657-87-1 chemical structure

Description

Compared with other compounds in its class, the molecular weight of 218.42 g/mol gives (2-Chloro-4-ethoxy-3-fluorophenyl)boronic acid distinctive chromatographic separation conditions and mass-spectrometry parameter settings.

CATO supplies (2-Chloro-4-ethoxy-3-fluorophenyl)boronic acid (CAS 2415657-87-1), a certified reference material (molecular formula C8H9BClFO3, MW 218.42 g/mol) for analytical method development and quality control.

(2-Chloro-4-ethoxy-3-fluorophenyl)boronic acid (C8H9BClFO3) contains a carboxylic acid group, a hydroxyl group, an ether linkage, fluorine/chlorine substitution. It is notably hygroscopic, halogen substitution raises its density and boiling point, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

As a certified reference material (CRM), (2-Chloro-4-ethoxy-3-fluorophenyl)boronic acid meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.

Physical & Chemical Properties

Molecular FormulaC8H9BClFO3
Molecular Weight218.42 g/mol
Purity97%+
StorageStore in a cool place (≤25°C), keep sealed and dry, keep tightly closed to prevent evaporation
Solubility (reference)Soluble in methanol, ethanol, DMSO
StabilityMay oxidize slowly on prolonged air exposure; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions
Degree of Unsaturation (DBE)3.5
UV AbsorptionUV-absorbing
CAS Registry Year (est.)2000
Halogen ContentF/Cl-containing

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