4-(Dimethylphosphoryl)picolinonitrile CAS 2416236-38-7
| CAS No. | 2416236-38-7 |
| Molecular Formula | C8H9N2OP |
| Molecular Weight | 180.14 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Structurally, 4-(Dimethylphosphoryl)picolinonitrile (C8H9N2OP) contains a nitrogen-containing heterocyclic scaffold, an amide group, organophosphorus functionality, a hydroxyl group, an ether linkage. The molecule exhibits a degree of unsaturation (DBE) of 5.5, corresponding to approximately 5 ring(s) or double-bond equivalent(s). With a molecular weight of 180.14 g/mol, it falls into the medium-molecular-weight range. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
4-(Dimethylphosphoryl)picolinonitrile (CAS 2416236-38-7) is a high-purity analytical reference standard with the molecular formula C8H9N2OP and a molecular weight of 180.14 g/mol.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C8H9N2OP |
| Molecular Weight | 180.14 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (faint amine-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 5.5 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2000 |
| Nitrogen Atoms | 2 |
Related Dimethylphosphoryl Standards
- 3-(Dimethylphosphoryl)picolinonitrile (CAS 2551117-29-2)
- 5-(Dimethylphosphoryl)nicotinonitrile (CAS 2580186-64-5)
- 5-(Dimethylphosphoryl)picolinonitrile (CAS 2551114-38-4)
- 6-(Dimethylphosphoryl)nicotinonitrile (CAS 2613384-19-1)
- 3-(Dimethylphosphoryl)benzonitrile (CAS 1333230-29-7)
- 2-(Dimethylphosphoryl)benzonitrile (CAS 1333230-30-0)
- 4-(Dimethylphosphoryl)benzonitrile (CAS 61738-49-6)
- 5-(Dimethylphosphoryl)pyrimidine-2-carbonitrile (CAS 2503202-14-8)
Recommended Standards
- 4-Fluoro-1H-benzo[d]imidazole-2-carboxylic acid (CAS 83431-74-7)
- 2-Methoxy-5-Nitrobenzenediazonium (CAS 27165-17-9)
- 4-Fluoro-1H-pyrrolo[2,3-c]pyridine-7-carboxylic acid (CAS 446284-56-6)
- 2-Butoxy-1,3,2-dioxaphospholane 2-oxide (CAS 67554-09-0)
- 2-Aminocyclohexan-1-ol hydrochloride (CAS 89584-01-0)
- (R)-4-(1-Amino-2,2,2-trifluoroethyl)benzonitrile (CAS 1212926-88-9)
- 5,4’-Dihydroxy-7-methoxy-6-methylflavane (CAS 770729-34-5)
- 2-Bromo-6-isothiocyanatopyridine (CAS 1192812-99-9)
- 2-(tert-Butyl)-6,7-dihydro-5H-pyrrolo[3,4-d]-pyrimidine (CAS 1211584-40-5)
- (R)-tert-Butyl 3-(pyridin-2-ylamino)piperidine-1-carboxylate (CAS 1255533-88-0)
- 2-Methyl-4-(4-nitrophenyl)thiazole (CAS 33102-81-7)
- Nebivolol Impurity 57 (CAS 1346562-35-3 (free base))
- N,N-dimethyl-2-(pyridin-3-yl)thiazole-4-carboxamide (CAS 338396-89-7)
- Semaglutide impurity 286 (CAS CATO-C4X-2226286)
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