6-Chloro-5-isopropyl-1H-indazol-3-amine CAS 2416992-41-9
| CAS No. | 2416992-41-9 |
| Molecular Formula | C10H12ClN3 |
| Molecular Weight | 209.68 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
CATO supplies 6-Chloro-5-isopropyl-1H-indazol-3-amine (CAS 2416992-41-9), a certified reference material (molecular formula C10H12ClN3, MW 209.68 g/mol) for analytical method development and quality control.
The molecular framework of 6-Chloro-5-isopropyl-1H-indazol-3-amine (C10H12ClN3) is characterized by a nitrogen-containing heterocyclic scaffold, a nitrile group, chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C10H12ClN3 |
| Molecular Weight | 209.68 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 6.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2000 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 3 |
Related Chloro Standards
- 6-Chloro-2-isopropyl-4-methyl-2h-pyrazolo[3,4-b]pyridine (CAS 1018046-39-3)
- 6-Chloro-4-methyl-2-propyl-2H-pyrazolo[3,4-b]pyridine (CAS 1018048-12-8)
- 5-Chloro-3-isopropyl-2-methyl-3H-imidazo[4,5-b]pyridine (CAS 1044770-70-8)
- 5-Chloro-1-isopropyl-1H-benzo[d]imidazol-2-amine (CAS 1154369-65-9)
- 1-(5-Chloro-1h-benzo[d]imidazol-2-yl)propan-1-amine (CAS 1156769-41-3)
- (5-Chloro-1-ethyl-1H-benzo[d]imidazol-2-yl)methanamine (CAS 1183898-37-4)
- 1-(5-Chloro-1-methyl-1H-benzo[d]imidazol-2-yl)ethan-1-amine (CAS 1184272-02-3)
- 3-(6-Chloro-1H-indazol-3-yl)propan-1-amine (CAS 118511-98-1)
Recommended Standards
- 5-Chloro-3-(2,5-dimethyl-1H-pyrrol-1-yl)-1-methyl-1H-pyrazole (CAS 89088-52-8)
- 6-Chloro-N,2-dicyclopropylpyrimidin-4-amine (CAS 617716-49-1)
- 5-Chloro-2-(1,4,5,6-tetrahydropyrimidin-2-yl)aniline (CAS 917750-14-2)
- 7-Chloro-1-propyl-1H-benzo[d]imidazol-2-amine (CAS 945024-43-1)
- 5-(chloromethyl)-3-(2-methoxyphenyl)-1,2,4-oxadiazole (CAS 110704-43-3)
- {3-[(Methylthio)methyl]-1,2,4-oxadiazol-5-yl}methylamine hydrochloride (CAS 915920-09-1)
- 4-(3,3-Dimethylbutyl)aniline (CAS 241499-52-5)
- methyl 3-hydroxy-5-(1H-pyrazol-1-yl)thiophene-2-carboxylate (CAS 113387-75-0)
- 1-(2,2-difluoroethyl)-1,2,3,4-tetrahydroquinolin-5-amine (CAS 1179290-21-1)
- Poly(1,4-butanediol)bis(4-aminobenzoate) (CAS 54667-43-5)
- (2S)-2-(1-oxo-2,3-dihydro-1H-isoindol-2-yl)propanoic acid (CAS 180923-78-8)
- 2-(Bromomethyl)-7-ethylbenzo[d]oxazole (CAS 1803837-57-1)
- (E)-4-((Benzylthio)methylene)-3-methylisoxazol-5(4H)-one (CAS 61861-47-0)
- Peptide Impurity 05 (CAS 2322924-83-2)
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