4-(Hydroxymethyl)-2,3,5,6-tetrafluoropyridine CAS 24191-31-9
| CAS No. | 24191-31-9 |
| Molecular Formula | C6H3F4NO |
| Molecular Weight | 181.09 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
As a certified reference material (CRM), 4-(Hydroxymethyl)-2,3,5,6-tetrafluoropyridine meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
4-(Hydroxymethyl)-2,3,5,6-tetrafluoropyridine (CAS 24191-31-9) is a high-purity analytical reference standard with the molecular formula C6H3F4NO and a molecular weight of 181.09 g/mol.
Structurally, 4-(Hydroxymethyl)-2,3,5,6-tetrafluoropyridine (C6H3F4NO) contains an amide group, a hydroxyl group, an ether linkage, fluorine substitution, an aromatic ring system. The molecule exhibits a degree of unsaturation (DBE) of 4.0, corresponding to approximately 4 ring(s) or double-bond equivalent(s). With a molecular weight of 181.09 g/mol, it falls into the medium-molecular-weight range. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
Physical & Chemical Properties
| Molecular Formula | C6H3F4NO |
| Molecular Weight | 181.09 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 4.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1963 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 1 |
Related Hydroxymethyl Standards
- Methyl (2-(hydroxymethyl)phenyl)carbamate (CAS 117550-36-4)
- Ethyl 2-(hydroxymethyl)nicotinate (CAS 1346539-22-7)
- Methyl 6-(hydroxymethyl)-5-methylnicotinate (CAS 1360960-26-4)
- 4-(Hydroxymethyl)-N-methoxybenzamide (CAS 1490569-21-5)
- 3-(6-(Hydroxymethyl)pyridin-2-yl)oxetan-3-ol (CAS 1644345-96-9)
- 2-(Hydroxymethyl)-4,5,6,7-tetrahydro-1H-isoindole-1,3(2H)-dione (CAS 4887-42-7)
- 2-[3-(hydroxymethyl)phenoxy]acetamide (CAS 774195-26-5)
- 4-Hydroxymethyl-3,4-dihydro-2H-pyrano[3,2-b]pyridin-4-ol (CAS 405174-47-2)
Recommended Standards
- 3-Bromotetrahydro-2H-thiopyran (CAS 32358-86-4)
- 4-Amino-2,3,5,6-tetrafluorophenol (CAS 938-63-6)
- 2,3,5,6-Tetrafluoro-4-methoxypyridine (CAS 2375-90-8)
- 4-Bromothiane (CAS 32358-88-6)
- 2-(2-Methyl-1H-indol-1-yl)ethan-1-amine sulfate (CAS 1185568-62-0)
- 2-Cyano-N-(3,5-dimethylphenyl)-3-(3-methoxyphenyl)propanamide (CAS 1260998-03-5)
- Phenol, (1,1-dimethylethyl)-4-methyl- (CAS 25567-40-2)
- Salbutamol Impurity 207 (CAS CATO-C4X-1176207)
- 2-Bromo-4,5-dichloropyridine (CAS 1033203-42-7)
- (2S,6S)-2-Isopropyl-6-methylpiperidin-4-one (CAS 2165573-07-7)
- 3-(3-Chloro-5-(trifluoromethyl)pyridin-2-yl)-N-(3-methoxypropyl)propanamide (CAS 339099-94-4)
- n-(Pyridin-4-ylmethyl)-2-(tetrahydrofuran-2-yl)ethan-1-amine (CAS 1183840-97-2)
- 1-n-Cyclohexylbenzene-1,2-diamine (CAS 74628-31-2)
- Prolactin-Releasing Peptide (12-31) (human) (CAS 235433-36-0)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com