4',5-Dichloro-N-(4-fluoro-2-methylphenyl)-2-hydroxy-[1,1'-Biphenyl]-3-carboxamide CAS 24283-57-6
| CAS No. | 24283-57-6 |
| Molecular Formula | C20H14Cl2FNO2 |
| Molecular Weight | 390.24 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Compared with other compounds in its class, the molecular weight of 390.24 g/mol gives 4',5-Dichloro-N-(4-fluoro-2-methylphenyl)-2-hydroxy-[1,1'-Biphenyl]-3-carboxamide distinctive chromatographic separation conditions and mass-spectrometry parameter settings.
4',5-Dichloro-N-(4-fluoro-2-methylphenyl)-2-hydroxy-[1,1'-Biphenyl]-3-carboxamide (CAS 24283-57-6), molecular formula C20H14Cl2FNO2 and molecular weight 390.24 g/mol, is a CATO reference standard with documented purity and traceability.
Owing to a steroid core, an amide group, a hydroxyl group, an ether linkage, fluorine/chlorine substitution, 4',5-Dichloro-N-(4-fluoro-2-methylphenyl)-2-hydroxy-[1,1'-Biphenyl]-3-carboxamide is typically pale yellow to yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 390.24 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C20H14Cl2FNO2 |
| Molecular Weight | 390.24 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 13.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1963 |
| Halogen Content | F/Cl-containing |
| Nitrogen Atoms | 1 |
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Recommended Standards
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- tert-Butyl (4-iodo-7-methylbenzo[d]thiazol-2-yl)carbamate (CAS 2803283-82-9)
- 2-(2,6-dioxo-3-piperidyl)-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)isoindoline-1,3-dione (CAS 2229725-98-6)
- 5-Fluoro-1-(pyridin-2-yl)-1H-pyrazole-4-carbonitrile (CAS 1269293-12-0)
- (E)-N-(4-fluorobenzyl)-2-(p-tolyl)ethene-1-sulfonamide (CAS 339105-17-8)
- 4-Bromopyridin-2(1H)-One (CAS 947407-84-3)
- 2-(4-Bromo-3,5-dimethyl-1H-pyrazol-1-yl)ethano hydrazide 2-(4-bromo-3,5-dimethyl-1h-pyrazol-1-yl)ethano-hydrazide 2-(4-bromo-3,5-dimethyl-1h-pyrazol-1-yl)ethanohydrazide (4-bromo-3,5-dimethyl-pyrazol-1-yl)-acetic acid hydrazide 2-(4-bromo-3,5-dimethyl-1h-pyrazol-1-yl)-acetohydrazide 175137-56-1 (CAS 175137-56-1)
- Methyl 7,7-dimethyl-2-oxobicyclo[2.2.1]heptane-1-carboxylate (CAS 57566-30-0)
- N-BOc-n-benzyl-peg3-alcohol (CAS 2030118-13-7)
- Afatinib Impurity 50 (CAS 2413212-25-4)
- (6-Isopropyl-2-methylimidazo[2,1-b][1,3,4]thiadiazol-5-yl)methanol (CAS 1267798-65-1)
- 4-([1,1'-Biphenyl]-3-yl)-2-chloroquinazoline (CAS 1413365-66-8)
- Semaglutide Impurity 1(OtBu-Ste-D-γGlu(OtBu)-AEEA-AEEA-OH) (CAS CATO-C4X-22261)
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