(2Z,3Z)-Bis[(4-chlorophenyl)methylidene]butanedioic acid CAS 24290-05-9
| CAS No. | 24290-05-9 |
| Molecular Formula | C18H12Cl2O4 |
| Molecular Weight | 363.19 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
As a certified reference material (CRM), (2Z,3Z)-Bis[(4-chlorophenyl)methylidene]butanedioic acid meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
(2Z,3Z)-Bis[(4-chlorophenyl)methylidene]butanedioic acid (CAS 24290-05-9), molecular formula C18H12Cl2O4 and molecular weight 363.19 g/mol, is a CATO reference standard with documented purity and traceability.
(2Z,3Z)-Bis[(4-chlorophenyl)methylidene]butanedioic acid (C18H12Cl2O4) contains a flavonoid core, a hydroxyl group, an ether linkage, chlorine substitution. Halogen substitution raises its density and boiling point, its high carbon-to-hydrogen ratio confers good lipid solubility, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
Physical & Chemical Properties
| Molecular Formula | C18H12Cl2O4 |
| Molecular Weight | 363.19 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 12.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1963 |
| Halogen Content | Cl-containing |
Recommended Standards
- (S)-tert-Butyl 3-iodo-6-methyl-6,7-dihydropyrazolo[1,5-a]pyrazine-5(4H)-carboxylate (CAS 1967003-63-9)
- (5-(2-Chlorophenyl)isoxazol-3-yl)methyl (3-chlorophenyl)carbamate (CAS 866049-25-4)
- Tert-butyl (R)-3-iodo-6-methyl-6,7-dihydropyrazolo[1,5-a]pyrazine-5(4H)-carboxylate (CAS 1967003-57-1)
- [(3Z)-5-Chloro-1-[(4-chlorophenyl)methyl]-2-oxo-2,3-dihydro-1H-indol-3-ylidene]amino acetate (CAS 320420-90-4)
- 3-(3-Chlorophenyl)-2-methyl-5-(phenylthio)furan (CAS 941270-45-7)
- N-(3-(1H-imidazol-1-yl)propyl)-4-(2-(4-chlorophenyl)acetyl)-1H-pyrrole-2-carboxamide (CAS 478040-37-8)
- 6-Chloro-2-methyl-5-nitro-pyridine-3-carboxylic acid (CAS 1638765-04-4)
- 2-Bromo-1-(4-iodophenyl)propan-1-one (CAS 31867-48-8)
- 2-Amino-4-ethylphenol hydrochloride (CAS 79509-90-3)
- 2-(((3,4-Dimethylphenyl)amino)methyl)phenol (CAS 70301-51-8)
- 3-(Adamantan-1-yl)pentane-2,4-dione (CAS 102402-84-6)
- Ethyl 2,2-difluoro-3-hydroxy-3-phenylpropanoate (CAS 92207-60-8)
- 4-Chloro-2-[2-(4-methyl-4H-[1,2,4]triazol-3-ylsulfanyl)-acetylamino]-benzoic acid (CAS 565166-34-9)
- Peptide Impurity 64 (CAS CATO-CPTD788964)
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