3-(7-Bromo-4-fluoro-1-oxoisoindolin-2-yl)piperidine-2,6-dione CAS 2438243-28-6
| CAS No. | 2438243-28-6 |
| Molecular Formula | C13H10BrFN2O3 |
| Molecular Weight | 341.13 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including 3-(7-Bromo-4-fluoro-1-oxoisoindolin-2-yl)piperidine-2,6-dione.
3-(7-Bromo-4-fluoro-1-oxoisoindolin-2-yl)piperidine-2,6-dione (CAS 2438243-28-6), molecular formula C13H10BrFN2O3 and molecular weight 341.13 g/mol, is a CATO reference standard with documented purity and traceability.
The molecular framework of 3-(7-Bromo-4-fluoro-1-oxoisoindolin-2-yl)piperidine-2,6-dione (C13H10BrFN2O3) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine/bromine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
As a certified reference material (CRM), 3-(7-Bromo-4-fluoro-1-oxoisoindolin-2-yl)piperidine-2,6-dione meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C13H10BrFN2O3 |
| Molecular Weight | 341.13 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 9.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2000 |
| Halogen Content | F/Br-containing |
| Nitrogen Atoms | 2 |
Related Bromo Standards
- Methyl 10-bromo-9-fluoro-5,6-dihydrobenzo[f]imidazo[1,2-d][1,4]oxazepine-2-carboxylate (CAS 1451089-41-0)
- 2-(4-Bromo-phenyl)-6-trifluoromethyl-imidazo[1,2-a]pyridine (CAS 724742-88-5)
- 3-(4-bromo-5-fluoro-1-oxo-isoindolin-2-yl)piperidine-2,6-dione (CAS 2619512-24-0)
- 3-(4-Bromo-7-fluoro-1-oxoisoindolin-2-yl)piperidine-2,6-dione (CAS 2438239-34-8)
- 3-(5-bromo-4-fluoro-1-oxo-isoindolin-2-yl)piperidine-2,6-dione (CAS 2408391-89-7)
- 3-(5-bromo-6-fluoro-1-oxo-isoindolin-2-yl)piperidine-2,6-dione (CAS 2409005-96-3)
- 3-(5-Bromo-7-fluoro-1-oxoisoindolin-2-yl)piperidine-2,6-dione (CAS 2438240-68-5)
- 3-(6-Bromo-4-fluoro-1-oxoisoindolin-2-yl)piperidine-2,6-dione (CAS 2438240-69-6)
Recommended Standards
- 3-(6-Bromo-5-fluoro-1-oxoisoindolin-2-yl)piperidine-2,6-dione (CAS 2438240-74-3)
- 3-(7-Bromo-5-fluoro-1-oxoisoindolin-2-yl)piperidine-2,6-dione (CAS 2438243-24-2)
- 3-(7-Bromo-6-fluoro-1-oxoisoindolin-2-yl)piperidine-2,6-dione (CAS 2438243-30-0)
- 4-Bromo-2-(((4-fluoro-3-nitrophenyl)amino)methyl)phenol (CAS 868256-48-8)
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