6-Fluorobenzofuran CAS 24410-60-4
| CAS No. | 24410-60-4 |
| Molecular Formula | C8H5FO |
| Molecular Weight | 136.12 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including 6-Fluorobenzofuran.
6-Fluorobenzofuran (CAS 24410-60-4), molecular formula C8H5FO and molecular weight 136.12 g/mol, is a CATO reference standard with documented purity and traceability.
Structurally, 6-Fluorobenzofuran (C8H5FO) contains a hydroxyl group, an ether linkage, fluorine substitution, an aromatic ring system. The molecule exhibits a degree of unsaturation (DBE) of 6.0, corresponding to approximately 6 ring(s) or double-bond equivalent(s). With a molecular weight of 136.12 g/mol, it falls into the low-molecular-weight range. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C8H5FO |
| Molecular Weight | 136.12 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 6.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1963 |
| Halogen Content | F-containing |
Related Fluorobenzofuran Standards
- 2-Fluorobenzofuran (CAS 280551-95-3)
- 4-Fluorobenzofuran (CAS 24410-58-0)
- 5-Fluorobenzofuran (CAS 24410-59-1)
- 7-Fluorobenzofuran (CAS 24410-61-5)
- 5-Fluorobenzofuran-4-amine (CAS 1367925-65-2)
- 5-Fluorobenzofuran-7-amine (CAS 412349-15-6)
- 4-Fluorobenzofuran-3(2H)-one (CAS 911826-36-3)
- 5-Fluorobenzofuran-2(3H)-one (CAS 886985-48-4)
Recommended Standards
- 4-Fluorobicyclo[4.2.0]octa-1(6),2,4-trien-7-one (CAS 409060-44-2)
- ethyl 2-fluoro-3-hydroxy-propanoate (CAS 1993-92-6)
- L-Aspartic Acid-d3 (CAS 3842-25-9)
- 4-Ethynyl-2-fluorophenol (CAS 949114-29-8)
- 2-(4-Methoxyphenoxy)-6-methyl-5-phenylpyridine-3-carbonitrile (CAS 338423-75-9)
- Erucic anhydride (CAS 103213-60-1)
- 2-(4-Fluorobenzyl)-6,7-dihydro-5H-thiazolo[3,2-a]pyrimidin-3(2H)-one (CAS 1049144-01-5)
- (4-Amino-3-isopropyl-5-methylphenyl)dimethylphosphine oxide (CAS 2397624-07-4)
- Pioglitazone impurity 32 (CAS CATO-C4X-138332)
- 2-Amino-N-isobutylacetamide (CAS 590423-20-4)
- 2-(Isoindolin-2-yl)acetamide (CAS 1623-36-5)
- 2-(3-Aminopropyl)-6-(pyridin-2-yl)pyridazin-3(2h)-one (CAS 1283108-62-2)
- Hexahydro-2'3a-dimethylspiro[1,3-dithiolo[4,5-b]furan-2,3'(2'h)-furan] (CAS 38325-25-6)
- Semaglutide Impurity 75 (CAS CATO-C4X-2226175)
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