N-(3-((2,5,6-Trichloropyrimidin-4-yl)amino)phenyl)-3-(trifluoromethyl)benzamide CAS 244278-44-2

Purity 97%+In StockPharmaceutical Standards
CAS No.244278-44-2
Molecular FormulaC18H10Cl3F3N4O
Molecular Weight461.65 g/mol
CategoryPharmaceutical Standards / API Standards
AvailabilityIn Stock

Chemical Structure

N-(3-((2,5,6-Trichloropyrimidin-4-yl)amino)phenyl)-3-(trifluoromethyl)benzamide CAS 244278-44-2 chemical structure

Description

Owing to a steroid core, an amide group, a hydroxyl group, an ether linkage, fluorine/chlorine substitution, N-(3-((2,5,6-Trichloropyrimidin-4-yl)amino)phenyl)-3-(trifluoromethyl)benzamide is typically pale yellow to yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 461.65 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).

N-(3-((2,5,6-Trichloropyrimidin-4-yl)amino)phenyl)-3-(trifluoromethyl)benzamide (CAS 244278-44-2), molecular formula C18H10Cl3F3N4O and molecular weight 461.65 g/mol, is a CATO reference standard with documented purity and traceability.

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.

Physical & Chemical Properties

Molecular FormulaC18H10Cl3F3N4O
Molecular Weight461.65 g/mol
AppearancePale yellow to yellow crystalline powder. (slight halide-like odor, low volatility)
Purity97%+
StorageStore at room temperature, protect from light
Solubility (reference)Soluble in DMSO, DMF, methanol
StabilityMay oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light
Degree of Unsaturation (DBE)13.0
UV AbsorptionUV-absorbing
Structural FeaturesAromatic ring present
CAS Registry Year (est.)2025
Halogen ContentF/Cl-containing
Nitrogen Atoms4

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