Ethyl 4-oxo-8-(trifluoromethyl)-1,4-dihydroquinoline-2-carboxylate CAS 24433-71-4
| CAS No. | 24433-71-4 |
| Molecular Formula | C13H10F3NO3 |
| Molecular Weight | 285.22 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Owing to a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine substitution, Ethyl 4-oxo-8-(trifluoromethyl)-1,4-dihydroquinoline-2-carboxylate is typically pale yellow to yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 285.22 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
Ethyl 4-oxo-8-(trifluoromethyl)-1,4-dihydroquinoline-2-carboxylate (CAS 24433-71-4) is a high-purity analytical reference standard with the molecular formula C13H10F3NO3 and a molecular weight of 285.22 g/mol.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
As a certified reference material (CRM), Ethyl 4-oxo-8-(trifluoromethyl)-1,4-dihydroquinoline-2-carboxylate meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C13H10F3NO3 |
| Molecular Weight | 285.22 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 8.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1963 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 1 |
Recommended Standards
- Ethyl 4-oxo-7-(trifluoromethyl)-1,4-dihydroquinoline-3-carboxylate (CAS 71083-04-0)
- Ethyl 5-(3-(trifluoromethyl)phenyl)oxazole-2-carboxylate (CAS 2749600-65-3)
- Ethyl 4-oxo-6-(trifluoromethyl)-1,4-dihydroquinoline-3-carboxylate (CAS 71083-01-7)
- Ethyl 5-[3-(Trifluoromethyl)phenyl]isoxazole-3-carboxylate (CAS 871676-36-7)
- 4-Amino-5-bromo-3-(difluoromethyl)picolinaldehyde (CAS 1805339-03-0)
- 3-tert-butyl 5-methyl 7-fluoro-4,4-dimethyl-4H,5H-imidazo[1,5-a]quinoxaline-3,5-dicarboxylate (CAS 148858-31-5)
- N-(2,3-dihydro-1,4-benzodioxin-6-yl)-2-(methylamino)acetamide hydrochloride (CAS 1585254-72-3)
- (E)-2-(4-(2-(1H-Indazol-3-yl)vinyl)phenoxy)ethyl acetate (CAS 841258-16-0)
- (Mercaptomethyl)diphenylphosphineoxide (CAS 324753-14-2)
- S-(2-(Furan-2-yl)ethyl) ethanethioate (CAS 59020-91-6)
- 6-((3,4-Dimethylphenyl)(methyl)amino)-3-methylpyrimidine-2,4(1H,3H)-dione (CAS 41648-17-3)
- 4-(Hexylamino)butanenitrile (CAS 90068-89-6)
- 2,6-dichloro-N,N-dimethylpyridin-4-amine (CAS 175461-34-4)
- Semaglutide impurity 29 (CAS 110990-08-4)
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