5-Fluoro-2-vinylbenzeneboronic acid CAS 2446429-28-1
| CAS No. | 2446429-28-1 |
| Molecular Formula | C8H8BFO2 |
| Molecular Weight | 165.96 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including 5-Fluoro-2-vinylbenzeneboronic acid.
CATO supplies 5-Fluoro-2-vinylbenzeneboronic acid (CAS 2446429-28-1), a certified reference material (molecular formula C8H8BFO2, MW 165.96 g/mol) for analytical method development and quality control.
Owing to a carboxylic acid group, a hydroxyl group, an ether linkage, fluorine substitution, an aromatic ring system, 5-Fluoro-2-vinylbenzeneboronic acid is typically off-white to pale yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 165.96 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
CATO manufactures 5-Fluoro-2-vinylbenzeneboronic acid under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C8H8BFO2 |
| Molecular Weight | 165.96 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 4.5 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2000 |
| Halogen Content | F-containing |
Related Fluoro Standards
- (3-Fluoro-5-vinylphenyl)boronic acid (CAS 1232836-03-1)
- (R)-5-Fluoro-3-methylbenzo[c][1,2]oxaborol-1(3H)-ol (CAS 2739832-10-9)
- 5-Fluoro-3-methylbenzo[c][1,2]oxaborol-1(3H)-ol (CAS 905710-75-0)
- 6-fluoro-3,4-dihydro-1H-2,1-benzoxaborinin-1-ol (CAS 905710-55-6)
- 5-Fluoro-2-(trifluoromethyl)pyrimidine (CAS 100345-66-2)
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- 3-Fluoro-6-(trifluoromethyl)pyridazine (CAS 1206524-32-4)
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Recommended Standards
- 2-(3-Fluorophenyl)-1,3,2-dioxaborolane (CAS 718642-08-1)
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- (E)-(4-Fluorostyryl)boronic acid (CAS 460748-43-0)
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Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
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- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com