5-Fluoro-6-(trifluoromethyl)pyrimidin-4(3H)-one CAS 2446509-01-7
| CAS No. | 2446509-01-7 |
| Molecular Formula | C5H2F4N2O |
| Molecular Weight | 182.08 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
5-Fluoro-6-(trifluoromethyl)pyrimidin-4(3H)-one (CAS 2446509-01-7) is a high-purity analytical reference standard with the molecular formula C5H2F4N2O and a molecular weight of 182.08 g/mol.
The molecular framework of 5-Fluoro-6-(trifluoromethyl)pyrimidin-4(3H)-one (C5H2F4N2O) is characterized by an amide group, a hydroxyl group, an ether linkage, fluorine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
CATO manufactures 5-Fluoro-6-(trifluoromethyl)pyrimidin-4(3H)-one under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C5H2F4N2O |
| Molecular Weight | 182.08 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 4.0 |
| UV Absorption | UV-absorbing |
| CAS Registry Year (est.) | 2000 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 2 |
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- 3-Amino-4-fluoropicolinamide (CAS 1805741-35-8)
- 4-(4-Fluorophenyl)-N-(4-methoxyphenyl)thiazol-2-amine hydrobromide (CAS 1274903-77-3)
- 4-Isocyanato-2-piperidin-1-ylpyridine (CAS 898289-22-0)
- Peptide T (CAS 106362-32-7)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com