(S)-1-(D-Valyl)-4,4-difluoropyrrolidine-2-carbonitrile hydrochloride CAS 2446617-70-3
| CAS No. | 2446617-70-3 |
| Molecular Formula | C10H15F2N3O |
| Molecular Weight | N/A |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
(S)-1-(D-Valyl)-4,4-difluoropyrrolidine-2-carbonitrile hydrochloride (CAS 2446617-70-3), molecular formula C10H15F2N3OHCl and molecular weight 267.70 g/mol, is a CATO reference standard with documented purity and traceability.
The molecular framework of (S)-1-(D-Valyl)-4,4-difluoropyrrolidine-2-carbonitrile hydrochloride (C10H15F2N3OHCl) is characterized by an amide group, a hydroxyl group, an ether linkage, fluorine/chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
As a certified reference material (CRM), (S)-1-(D-Valyl)-4,4-difluoropyrrolidine-2-carbonitrile hydrochloride meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C10H15F2N3O HCl |
| Molecular Weight | 267.70 g/mol |
| Appearance | White to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 3.0 |
| UV Absorption | UV-absorbing |
| CAS Registry Year (est.) | 2000 |
| Halogen Content | F/Cl-containing |
| Nitrogen Atoms | 3 |
Recommended Standards
- N-(7H-Purin-6-yl)hydroxylamine (CAS 5667-20-9)
- 1-(2-Hydroxybenzoyl)pyrrolidine-2-carboxylic acid (CAS 70491-02-0)
- 3-4-6-Tri-O-acetyl-2-deoxy-2-phthalimido-β-D-glucopyranosyl chloride (CAS 7772-87-4)
- 3-(4-Benzylphenyl)isoxazol-5-amine (CAS 501902-13-2)
- (1,4-Diazepan-1-yl)(2-fluorophenyl)methanone hydrochloride (CAS 1170845-72-3)
- 2-(4-Bromophenyl)-1-(4-methylpiperidin-1-yl)ethanone (CAS 349430-29-1)
- 4-(1H-Pyrrolo[2,3-b]pyridin-3-yl)cyclohexanone (CAS 282547-13-1)
- 3-(2,3-Dihydrobenzo[b][1,4]dioxin-6-yl)-1-(p-tolyl)-1H-pyrazole-4-carbaldehyde (CAS 618098-94-5)
- Methyl 4-(aminomethyl)nicotinate (CAS 1260675-06-6)
- [D-His]-Semaglutide B (x TFA Salt) (CAS CATO-C4X-2226117)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com