(S)-1-(D-Alanyl)-4,4-difluoropyrrolidine-2-carbonitrile hydrochloride CAS 2446618-11-5
| CAS No. | 2446618-11-5 |
| Molecular Formula | C8H11F2N3O |
| Molecular Weight | N/A |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
(S)-1-(D-Alanyl)-4,4-difluoropyrrolidine-2-carbonitrile hydrochloride (CAS 2446618-11-5), molecular formula C8H11F2N3OHCl and molecular weight 239.65 g/mol, is a CATO reference standard with documented purity and traceability.
(S)-1-(D-Alanyl)-4,4-difluoropyrrolidine-2-carbonitrile hydrochloride (C8H11F2N3OHCl) contains an amide group, a hydroxyl group, an ether linkage, fluorine/chlorine substitution. Halogen substitution raises its density and boiling point; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C8H11F2N3O HCl |
| Molecular Weight | 239.65 g/mol |
| Appearance | White to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 3.0 |
| UV Absorption | UV-absorbing |
| CAS Registry Year (est.) | 2000 |
| Halogen Content | F/Cl-containing |
| Nitrogen Atoms | 3 |
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