2-(4-Chloro-1h-indol-3-yl)acetonitrile CAS 2447-15-6
| CAS No. | 2447-15-6 |
| Molecular Formula | C10H7ClN2 |
| Molecular Weight | 190.63 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
2-(4-Chloro-1h-indol-3-yl)acetonitrile (CAS 2447-15-6), molecular formula C10H7ClN2 and molecular weight 190.63 g/mol, is a CATO reference standard with documented purity and traceability.
Owing to a nitrogen-containing heterocyclic scaffold, a nitrile group, chlorine substitution, 2-(4-Chloro-1h-indol-3-yl)acetonitrile is typically pale yellow to yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 190.63 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
Physical & Chemical Properties
| Molecular Formula | C10H7ClN2 |
| Molecular Weight | 190.63 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, faint amine-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 8.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1957 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 2 |
Related Chloro Standards
- 2-Chloro-3,3'-bipyridine (CAS 101001-94-9)
- 6-Chloro-1-naphthaldehyde (CAS 116632-02-1)
- 4-Chloro-7-methyl-1H-indole-6-carbonitrile (CAS 1167056-04-3)
- 2-Chloro-3,4'-bipyridine (CAS 1187968-06-4)
- 5-chloro-1-methyl-1H,6H,7H-pyrazolo[4,3-d]pyrimidin-7-one (CAS 1211533-31-1)
- 4-Chloro-2,4'-bipyridine (CAS 1214335-54-2)
- 2-Chloro-N'-(2-cyclopropylacetyl)acetohydrazide (CAS 1263386-34-0)
- 2-Chloro-4-phenylpyrimidine (CAS 13036-50-5)
Recommended Standards
- 2-chloro-7H-pyrimido[5,4-d]pyrimidin-8-one (CAS 189747-31-7)
- 2-(5-Chloro-1H-indol-3-yl)acetonitrile (CAS 81630-83-3)
- 2'-Chloro-3,4'-bipyridine (CAS 171020-15-8)
- 2-(6-Chloro-1H-indol-3-yl)acetonitrile (CAS 61220-58-4)
- 1-Benzyl-5-(4-bromophenyl)-2-(methylthio)-1H-imidazole (CAS 1207043-06-8)
- Oxamic Acid Ammonium Salt (CAS 516-00-7)
- 2-[4-(1h-imidazol-1-ylmethyl)phenyl]benzoic acid (CAS 929972-79-2)
- N,N',N"-Tris(3-pyridinyl) phosphorothioic triamide (CAS 2146095-56-7)
- 2,6-Dibromo-4-chloro-3-fluoroaniline (CAS 1160574-58-2)
- tert-Butyl 4-(but-3-en-1-yl)piperidine-1-carboxylate (CAS 403857-14-7)
- 3,4-Dichloro-N-(2-nitrophenyl)benzo[b]thiophene-2-carboxamide (CAS 332382-11-3)
- (E)-3-Methoxyacrylic acid (CAS 6214-29-5)
- 3-(2-Chlorophenyl)-5-[(E)-2-[(3,5-dichlorophenyl)amino]ethenyl]-1,2-oxazole-4-carbonitrile (CAS 320425-17-0)
- Semaglutide impurity 203 (CAS CATO-C4X-2226203)
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