Rilpivirine Chloro Impurity CAS 244768-32-9
| CAS No. | 244768-32-9 |
| Molecular Formula | C11H7ClN4 |
| Molecular Weight | 230.65 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
CATO supplies Rilpivirine Chloro Impurity (CAS 244768-32-9), a pharmacopoeial impurity reference standard (molecular formula C11H7ClN4, MW 230.65 g/mol) used for the identification and quantification of trace impurities in APIs.
Rilpivirine Chloro Impurity (C11H7ClN4) contains a nitrogen-containing heterocyclic scaffold, a nitrile group, chlorine substitution. Halogen substitution raises its density and boiling point, its high carbon-to-hydrogen ratio confers good lipid solubility; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C11H7ClN4 |
| Molecular Weight | 230.65 g/mol |
| Purity | >95% |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 10.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 4 |
Related Rilpivirine Standards
- Rilpivirine Keto Impurity (CAS 189956-45-4)
- Rilpivirine Impurity 6 (CAS 1009330-41-9)
- Rilpivirine Nitrile Z-isomer (CAS 661489-22-1)
- Rilpivirine Impurity 4 (CAS 1629023-90-0)
- Rilpivirine Impurity 13 (CAS CATO-C4X-136313)
- Rac-Rilpivirine (CAS 620622-82-4)
- Rilpivirine (CAS 500287-72-9)
- Rilpivirine (Z-Isomer) (CAS 500287-94-5)
Recommended Standards
- 0757AE 2-(6-Chloro-3-pyridazinyl)-2-(2-pyridinyl)-acetonitrile 338779-25-2 C11H7ClN4 (CAS 338779-25-2)
- Opicapone impurity 27 (CAS CATO-C4X-240427)
- N-Deethylcyanazine amide (CAS 36556-77-1)
- N-Nitroso Simazine (CAS 6494-81-1)
- Tucatinib Impurity 7 (CAS CATO-C4X-26057)
- Folic Acid Impurity 40 HCl (CAS CATO-C4X-139540)
- Vardenafil Impurity N19 (CAS 2411340-39-9)
- N-Nitrosomorpholine-d8 (CAS 1219805-76-1)
- 2-Acetoxymethyl-5-hydroxymethyl-4-methoxy-3-methylpyridine (CAS 120003-77-2)
- 1-(4-Methyl-2-nitrophenyl)-5-oxopyrrolidine-3-carboxylic acid (CAS 1160264-10-7)
- 1-(bromomethyl)-3,4-dihydro-1H-2-benzopyran (CAS 99070-15-2)
- 1-((4-Chlorophenethyl)amino)propan-2-ol hydrochloride (CAS 1030624-41-9)
- Tris(ethylenediamine)chromium(III) chloride hemiheptahydrate, min. 98% (CAS 16165-32-5)
- Liraglutide(8-31)TFA Salt (CAS CATO-C4X-19922)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com