Tert-butyl 1-(hydroxymethyl)hexahydropyrrolo[3,4-c]pyrrole-2(1H)-carboxylate hydrochloride CAS 2448475-38-3
| CAS No. | 2448475-38-3 |
| Molecular Formula | C12H22N2O3 |
| Molecular Weight | N/A |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
Tert-butyl 1-(hydroxymethyl)hexahydropyrrolo[3,4-c]pyrrole-2(1H)-carboxylate hydrochloride (CAS 2448475-38-3), molecular formula C12H22N2O3HCl and molecular weight 278.78 g/mol, is a CATO reference standard with documented purity and traceability.
The molecular framework of Tert-butyl 1-(hydroxymethyl)hexahydropyrrolo[3,4-c]pyrrole-2(1H)-carboxylate hydrochloride (C12H22N2O3HCl) is characterized by an amide group, a carboxylic acid group, a hydroxyl group, an ether linkage, chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C12H22N2O3 HCl |
| Molecular Weight | 278.78 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 2.0 |
| CAS Registry Year (est.) | 2000 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 2 |
Recommended Standards
- 3-Azabicyclo[3.2.0]heptane-3-carbonyl chloride (CAS 623580-00-7)
- 2-Amino-6-chloronicotinaldehyde (CAS 58584-61-5)
- 4-(4-Chlorophenyl)-3-methyl-1-phenylindeno[1,2-b]pyrazolo[4,3-e]pyridin-5(1H)-one (CAS 1009630-24-3)
- Ethyl 3-(4-methoxyphenyl)propiolate (CAS 51718-85-5)
- N-(2-Bromoethyl)-3,5-difluorobenzenesulfonamide (CAS 942473-84-9)
- Methyl 3-iodo-4-phenoxybenzoate (CAS 100725-29-9)
- N-hydroxy-3-methyl-2,4-dioxo-1-phenyl-1,2,3,4-tetrahydropyrimidine-5-carboximidamide (CAS 499769-98-1)
- Oxacillin EP Impurity G (CAS CATO-C4X-232121)
- Micafungin Impurity 4 (CAS 179162-55-1)
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