2,4-Dimethyl-5-[(1,2-dihydro-2-oxo-3h-indol-3-ylidenE)methyl]-pyrrole-3-propanoicacid CAS 245036-27-5
| CAS No. | 245036-27-5 |
| Molecular Formula | C18H18N2O3 |
| Molecular Weight | 310.35 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
2,4-Dimethyl-5-[(1,2-dihydro-2-oxo-3h-indol-3-ylidenE)methyl]-pyrrole-3-propanoicacid (CAS 245036-27-5) is a high-purity analytical reference standard with the molecular formula C18H18N2O3 and a molecular weight of 310.35 g/mol.
The molecular framework of 2,4-Dimethyl-5-[(1,2-dihydro-2-oxo-3h-indol-3-ylidenE)methyl]-pyrrole-3-propanoicacid (C18H18N2O3) is characterized by a steroid core, an amide group, a hydroxyl group, an ether linkage. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
As a certified reference material (CRM), 2,4-Dimethyl-5-[(1,2-dihydro-2-oxo-3h-indol-3-ylidenE)methyl]-pyrrole-3-propanoicacid meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C18H18N2O3 |
| Molecular Weight | 310.35 g/mol |
| Appearance | Pale yellow to yellow crystalline powder |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 11.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Nitrogen Atoms | 2 |
Related Dimethyl Standards
- (Z)-3-(2,4-Dimethyl-5-((2-oxoindolin-3-ylidene)methyl)-1H-pyrrol-3-yl)propanoic acid (SU-6668) (CAS 210644-62-5)
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Recommended Standards
- 2,2':6',2'':6'',2'''-Quaterpyridine (CAS 4392-83-0)
- 2,5-Dipropoxyterephthalohydrazide (CAS 2143456-42-0)
- 2,2',3,3'-Tetrahydro-[5,5'-bithieno[3,4-b][1,4]dioxine]-7-carbaldehyde (CAS 336607-95-5)
- 2,6-Diphenylbenzo[1,2-b:4,5-b']difuran (CAS 5379-77-1)
- (S)-2-((S)-1-((S)-2-((S)-2-Aminopropanamido)propanoyl)pyrrolidine-2-carboxamido)pentanedioic acid (CAS 654067-61-5)
- Ethyl 2-amino-3-cyano-4-methyl-4,5,6,7-tetrahydrobenzo[b]thiophene-4-carboxylate (CAS 175599-84-5)
- N-(6-Amino-2,4-dioxo-1,2,3,4-tetrahydropyrimidin-5-yl)formamide (CAS 10184-00-6)
- tert-Butyl (2,4-dibromo-5-methoxyphenyl)carbamate (CAS 1876328-62-9)
- H-Ser-Ile-Gly-Ser-Leu-Ala-Lys-OH (CAS 115918-58-6)
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- Imastaxime Impurity 2 (CAS CATO-C4X-31352)
- 8-(Tert-butyl) 1-methyl 8-azaspiro[4.5]Decane-1,8-dicarboxylate (CAS 2387274-19-1)
- N-Cyclohexyl-N-methylaniline (CAS 18707-43-2)
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