4-(2-Chlorophenoxy)piperidine CAS 245057-65-2
| CAS No. | 245057-65-2 |
| Molecular Formula | C11H14ClNO |
| Molecular Weight | 211.69 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The molecular framework of 4-(2-Chlorophenoxy)piperidine (C11H14ClNO) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
CATO supplies 4-(2-Chlorophenoxy)piperidine (CAS 245057-65-2), a certified reference material (molecular formula C11H14ClNO, MW 211.69 g/mol) for analytical method development and quality control.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C11H14ClNO |
| Molecular Weight | 211.69 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 5.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 1 |
Related Chlorophenoxy Standards
- 2-((3-Chlorophenoxy)methyl)pyrrolidine (CAS 1248691-20-4)
- 2-(4-Chlorophenoxy)-1-cyclopropylethan-1-amine (CAS 1342169-99-6)
- (S)-2-((4-chlorophenoxy)methyl)pyrrolidine (CAS 220510-63-4)
- 2-((2-Chlorophenoxy)methyl)pyrrolidine (CAS 883520-71-6)
- 2-((4-Chlorophenoxy)methyl)pyrrolidine (CAS 383127-72-8)
- 3-((3-Chlorophenoxy)methyl)pyrrolidine (CAS 914299-54-0)
- 3-(2-Chlorophenoxy)piperidine (CAS 902837-29-0)
- 3-(3-Chlorophenoxy)piperidine (CAS 902837-32-5)
Recommended Standards
- 4-(2-Chlorobenzyl)morpholine (CAS 415932-72-8)
- 4-(2-Chlorophenyl)piperazin-1-amine (CAS 935260-76-7)
- 3-Chloro-N-isobutylbenzamide (CAS 26163-88-2)
- 4-(3-Chlorophenoxy)piperidine (CAS 97840-40-9)
- 2-Fluoro-3-(trifluoromethoxy)benzoyl chloride (CAS 948294-35-7)
- 1-(2-(Trifluoromethoxy)benzyl)azetidin-3-amine (CAS 1484666-19-4)
- 2,2,5,5-Tetramethyl-1,2,5-azadisilolidine (CAS 7418-19-1)
- 2-Amino-N-methylbenzamide (CAS 4141-08-6)
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