Ethyl 2-(difluoromethyl)imidazo[1,2-a]pyridine-3-carboxylate CAS 2451256-48-5
| CAS No. | 2451256-48-5 |
| Molecular Formula | C11H10F2N2O2 |
| Molecular Weight | 240.21 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including Ethyl 2-(difluoromethyl)imidazo[1,2-a]pyridine-3-carboxylate.
CATO supplies Ethyl 2-(difluoromethyl)imidazo[1,2-a]pyridine-3-carboxylate (CAS 2451256-48-5), a certified reference material (molecular formula C11H10F2N2O2, MW 240.21 g/mol) for analytical method development and quality control.
Structurally, Ethyl 2-(difluoromethyl)imidazo[1,2-a]pyridine-3-carboxylate (C11H10F2N2O2) contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine substitution. The molecule exhibits a degree of unsaturation (DBE) of 7.0, corresponding to approximately 7 ring(s) or double-bond equivalent(s). With a molecular weight of 240.21 g/mol, it falls into the medium-molecular-weight range. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
As a certified reference material (CRM), Ethyl 2-(difluoromethyl)imidazo[1,2-a]pyridine-3-carboxylate meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C11H10F2N2O2 |
| Molecular Weight | 240.21 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 7.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2000 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 2 |
Related Ethyl Standards
- (4-(5-(Difluoromethyl)pyridin-2-yl)-1-methyl-1H-1,2,3-triazol-5-yl)methanol (CAS 2760882-48-0)
- 4-(Difluoromethyl)-6-fluoro-5-methylpyridine-3-sulfonamide (CAS 1804423-52-6)
- 4-(Difluoromethyl)-5-fluoro-3-methylpyridine-2-sulfonamide (CAS 1804423-64-0)
- 4-(Difluoromethyl)-5-fluoro-2-methylpyridine-3-sulfonamide (CAS 1804423-68-4)
- 2-(Difluoromethyl)-6-fluoro-3-methylpyridine-5-sulfonamide (CAS 1804945-02-5)
- 4-(Difluoromethyl)-2-fluoro-6-methylpyridine-3-sulfonamide (CAS 1804945-65-0)
- 2-(Difluoromethyl)-6-fluoro-3-methylpyridine-4-sulfonamide (CAS 1805294-86-3)
- 2-(Difluoromethyl)-6-fluoro-5-methylpyridine-3-sulfonamide (CAS 1805442-96-9)
Recommended Standards
- Ethyl 2-(6-methoxy-3-nitropyridin-2-yl)acetate (CAS 450357-78-5)
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- Dimethyl 4-hydroxy-5-methoxyphthalate (CAS 50522-17-3)
- Ethyl 4-oxo-3-(propionyloxy)-4H-pyran-2-carboxylate (CAS 2061980-23-0)
- Quinoline-3,4-diamine (CAS 87751-33-5)
- Geranyl acetate (CAS 16409-44-2)
- 2-(3-Aminopyrrolidin-1-yl)-6-(methoxymethyl)-3-methylpyrimidin-4(3H)-one (CAS 1710845-30-9)
- 7-Chloro-3-(3-fluorophenyl)-3,4-dihydro-2H-benzo[b][1,4]oxazine (CAS 1707571-78-5)
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- Methyl 2-amino-4-(3-methoxyphenyl)pyrimidine-5-carboxylate (CAS 1187385-80-3)
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