(3E)-3-(Phenylmethylidene)-3,4-dihydro-2H-1-benzopyran-4-one CAS 24513-66-4
| CAS No. | 24513-66-4 |
| Molecular Formula | C16H12O2 |
| Molecular Weight | 236.27 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The molecular framework of (3E)-3-(Phenylmethylidene)-3,4-dihydro-2H-1-benzopyran-4-one (C16H12O2) is characterized by a carboxylic acid group, a hydroxyl group, an ether linkage, a polycyclic aromatic system. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.
(3E)-3-(Phenylmethylidene)-3,4-dihydro-2H-1-benzopyran-4-one (CAS 24513-66-4), molecular formula C16H12O2 and molecular weight 236.27 g/mol, is a CATO reference standard with documented purity and traceability.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
As a certified reference material (CRM), (3E)-3-(Phenylmethylidene)-3,4-dihydro-2H-1-benzopyran-4-one meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C16H12O2 |
| Molecular Weight | 236.27 g/mol |
| Appearance | Pale yellow to yellow crystalline powder |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 11.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1964 |
Related E Standards
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- (3Z)-3-(Phenylmethylidene)-2,3-dihydro-1H-indol-2-one (CAS 23772-61-4)
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Recommended Standards
- (3-Amino-4-methoxyphenyl)(morpholino)methanone (CAS 926211-47-4)
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- (3-Amino-2-hydroxyphenyl)(4-hydroxypiperidin-1-yl)methanone (CAS 473731-25-8)
- (5-Nitro-2-(piperidin-1-yl)phenyl)methanol (CAS 203509-89-1)
- 1-(4-(Methylthio)benzo[d]thiazol-2-yl)-3-(thiophen-2-ylmethyl)urea (CAS 1251574-83-0)
- 3-Bromo-5-chloro-4,6-dimethylpyridin-2-amine (CAS 1823905-59-4)
- Fmoc-PEG1-CH2CH2-NHS ester (CAS 1807521-05-6)
- N-Pentylcyclopentanamine (CAS 70391-99-0)
- (S)-2-((((9H-fluoren-9-yl)methoxy)carbonyl)amino)-3-(3-chloro-5-fluorophenyl)propanoic acid (CAS 1998650-51-3)
- Piracetam Impurity 9 (CAS CATO-C4X-12359)
- Methyl 3-(3,5-dimethylphenyl)propanoate (CAS 103234-48-6)
- Cholic Acid Impurity 83 (CAS CATO-C4X-116083)
- 1-(aminomethyl)-3,3-difluoro-cyclobutanol;hydrochloride (CAS 2316459-28-4)
- Semaglutide Impurity 123 (CAS 71997-93-8)
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