2-Chloro-6-iodo-4-methoxy-3-methylbenzoic acid CAS 2451906-54-8
| CAS No. | 2451906-54-8 |
| Molecular Formula | C9H8ClIO3 |
| Molecular Weight | 326.52 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including 2-Chloro-6-iodo-4-methoxy-3-methylbenzoic acid.
2-Chloro-6-iodo-4-methoxy-3-methylbenzoic acid (CAS 2451906-54-8), molecular formula C9H8ClIO3 and molecular weight 326.52 g/mol, is a CATO reference standard with documented purity and traceability.
2-Chloro-6-iodo-4-methoxy-3-methylbenzoic acid (C9H8ClIO3) contains a carboxylic acid group, a hydroxyl group, an ether linkage, chlorine/iodine substitution, an aromatic ring system. It is notably hygroscopic, halogen substitution raises its density and boiling point, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C9H8ClIO3 |
| Molecular Weight | 326.52 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), keep sealed and dry |
| Solubility (reference) | Soluble in methanol, ethanol, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 5.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2000 |
| Halogen Content | Cl/I-containing |
Related Chloro Standards
- Methyl 4-chloro-5-iodo-2-methoxybenzoate (CAS 1629269-31-3)
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- 3-Chloro-2-fluoro-4-iodo-6-(pyrrolidin-1-yl)-pyridine (CAS 1228666-54-3)
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Recommended Standards
- 11-benzyl-10-sulfanyl-7-thia-9,11-diazatricyclo[6.4.0.0²,⁶]dodeca-1(8),2(6),9-trien-12-one (CAS 351342-01-3)
- 4-cyclopentyl-11-methyl-5-sulfanyl-8-thia-4,6-diazatricyclo[7.4.0.0²,⁷]trideca-1(9),2(7),5-trien-3-one (CAS 757221-99-1)
- Ethyl 4-amino-6-chloro-5-iodonicotinate (CAS 1935952-84-3)
- 5-([2-[(5-Mercapto-1,3,4-thiadiazol-2-yl)thio]ethyl]thio)-1,3,4-thiadiazole-2-thiol (CAS 10486-54-1)
- 4-(2,5-Difluorophenyl)pyrrolidin-2-one (CAS 1470554-60-9)
- 6-Chloro-2-(2-propoxyphenyl)quinoline-4-carbonyl chloride (CAS 1160263-47-7)
- 2-(3,4-Dihydroxy-phenyl)-5,7-dihydroxy-3-methoxy-8-((E)-3-methyl-but-2-enyl)-6-(3-methyl-but-2-enyl)-1-benzopyran-4-one 2-(3,4-dihydroxyphenyl)-5,7-dihydroxy-3-methoxy-6,8-bis(3-methylbut-2-enyl)chromen-4-one 99217-70-6 Broussoflavanol B (CAS 99217-70-6)
- ((2-Bromocyclopentyl)oxy)cyclohexane (CAS 1251095-53-0)
- 2-Acetamido-2-[(4-methoxyphenyl)carbamoyl]acetic acid (CAS 866018-00-0)
- tert-Butyl (3-isopropyl-4-oxo-1,3,7-triazaspiro[4.4]non-1-en-2-yl)carbamate oxalate (CAS 1956426-55-3)
- 2,4-Diamino-6-(dimethylamino)pyrimidine-5-carbonitrile (CAS 343375-96-2)
- Procaterol Impurity 21 (CAS CATO-C4X-181021)
- 2-Amino-7-hydroxy-1,2,3,4-tetrahydronaphthalene-2-carboxylic acid (CAS 741614-51-7)
- Semaglutide impurity 211 (CAS CATO-C4X-2226211)
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