7-Bromo-5-fluoro-2,2-dimethyl-2,3-dihydrobenzo[b][1,4]dioxine-6-carboxylic acid CAS 2451907-95-0
| CAS No. | 2451907-95-0 |
| Molecular Formula | C11H10BrFO4 |
| Molecular Weight | 305.10 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Compared with other compounds in its class, the molecular weight of 305.10 g/mol gives 7-Bromo-5-fluoro-2,2-dimethyl-2,3-dihydrobenzo[b][1,4]dioxine-6-carboxylic acid distinctive chromatographic separation conditions and mass-spectrometry parameter settings.
7-Bromo-5-fluoro-2,2-dimethyl-2,3-dihydrobenzo[b][1,4]dioxine-6-carboxylic acid (CAS 2451907-95-0) is a high-purity analytical reference standard with the molecular formula C11H10BrFO4 and a molecular weight of 305.10 g/mol.
The molecular framework of 7-Bromo-5-fluoro-2,2-dimethyl-2,3-dihydrobenzo[b][1,4]dioxine-6-carboxylic acid (C11H10BrFO4) is characterized by a carboxylic acid group, a hydroxyl group, an ether linkage, fluorine/bromine substitution, an aromatic ring system. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
CATO manufactures 7-Bromo-5-fluoro-2,2-dimethyl-2,3-dihydrobenzo[b][1,4]dioxine-6-carboxylic acid under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C11H10BrFO4 |
| Molecular Weight | 305.10 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in methanol, ethanol, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 6.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2000 |
| Halogen Content | F/Br-containing |
Related Bromo Standards
- 4-Bromo-3-fluoro-6-nitro-2-(tetrahydrofuran-2-yl)aniline (CAS 1384984-27-3)
- 2-Bromo-6-fluoroanthracene-9,10-dione (CAS 919992-02-2)
- 7-Bromo-5-fluoro-3,3-dimethyl-2,3-dihydrobenzo[b][1,4]dioxine-6-carboxylic acid (CAS 2451907-99-4)
- Ethyl 2-(3-bromo-2-fluoro-6-formylphenoxy)acetate (CAS 2366994-69-4)
- Ethyl 2-(4-bromo-2-fluoro-6-formylphenoxy)acetate (CAS 2161554-52-3)
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- 5-Bromo-1-(4-(trifluoromethyl)benzyl)-1H-Pyrazole (CAS 1057383-73-9)
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Recommended Standards
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- 1,4,5,6,7,8-Hexafluoro-3-(trifluoromethyl)isoquinoline (CAS 63485-11-0)
- 4-[(4-iodophenyl)amino]butanoic acid (CAS 1039879-15-6)
- Mono-n-heptyltriethyltin (CAS 51283-39-7)
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- 4-(2,2-Dimethyl-5-oxotetrahydrofuran-3-yl)butanoic acid (CAS 6266-61-1)
- Ethyl 2-(3-cyclopropyl-4-(difluoromethyl)-6-(1,5-dimethyl-1H-pyrazol-4-yl)-1H-pyrazolo[3,4-b]pyridin-1-yl)acetate (CAS 1171643-63-2)
- 5-Iodo-1H-pyrazolo[3,4-c]pyridine (CAS 1033772-25-6)
- 5-Fluoro-4-iodopyridin-2(1H)-one (CAS 1227576-86-4)
- 2-Nitro-N-(1-phenylethyl)aniline (CAS 31488-84-3)
- 2-(Naphthalen-1-yl)ethanamine (CAS 4735-50-6)
- 3-(4-Chlorophenyl)-5-(methylsulfanyl)-2-thiophenecarboxylic acid (CAS 203189-46-2)
- (2-Cyclobutyl-6-fluoropyridin-4-yl)boronic acid (CAS 2225177-19-3)
- Hexapeptide-9 (CAS 885024-94-2)
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