4,7-Dichloro-2-(difluoromethyl)-8-fluoropyrido[4,3-d]pyrimidine CAS 2454491-29-1
| CAS No. | 2454491-29-1 |
| Molecular Formula | C8H2Cl2F3N3 |
| Molecular Weight | 268.02 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
4,7-Dichloro-2-(difluoromethyl)-8-fluoropyrido[4,3-d]pyrimidine (CAS 2454491-29-1), molecular formula C8H2Cl2F3N3 and molecular weight 268.02 g/mol, is a CATO reference standard with documented purity and traceability.
Based on its molecular formula C8H2Cl2F3N3, 4,7-Dichloro-2-(difluoromethyl)-8-fluoropyrido[4,3-d]pyrimidine contains a nitrogen-containing heterocyclic scaffold, a nitrile group, fluorine/chlorine substitution; these features give the compound characteristic absorption bands in UV spectroscopy. The molecular weight of 268.02 g/mol is directly relevant to the identification of the molecular ion in mass spectrometry. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C8H2Cl2F3N3 |
| Molecular Weight | 268.02 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 7.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2000 |
| Halogen Content | F/Cl-containing |
| Nitrogen Atoms | 3 |
Related Dichloro Standards
- 2,4-Dichloro-7-(trifluoromethyl)pyrido[2,3-d]pyrimidine (CAS 1220518-13-7)
- 2,4-Dichloro-6-(trifluoromethyl)pyrido[3,2-d]pyrimidine (CAS 1260663-64-6)
- Methyl 2,4-dichloro-5-fluoro-3-nitrobenzoate (CAS 1153285-12-1)
- 1-(2,2-Dichloro-1,1-Difluoroethoxy)-4-Isocyanatobenzene (CAS 55225-96-2)
- 2,4-Dichloro-6-(2,2-difluoro-propoxy)-pyrimidine-5-carbonitrile (CAS 1965309-20-9)
- 4,6-Dichloro-2-(2,2-difluoro-propoxy)-pyrimidine-5-carbonitrile (CAS 1965309-21-0)
- 2,4-Dichloro-6-nitroquinoline-3-carbonitrile (CAS 113944-49-3)
- 2,4-Dichloro-3-nitroquinoline-6-carbonitrile (CAS 1447961-33-2)
Recommended Standards
- 2-Fluoro-3-iodo-6-methoxyphenol (CAS 2385731-55-3)
- 4-Fluoro-3-iodo-5-methoxyphenol (CAS 2385485-76-5)
- 2-bromo-1-(3,3-dinitroazetidin-1-yl)ethanone (CAS 925206-65-1)
- Pyrido[2,3-d]pyridazine, 5,8-dichloro-2-(trifluoromethyl)- (CAS 2890563-14-9)
- N-(2-chlorophenyl)nicotinamide (CAS 75075-31-9)
- Methyl 2-amino-3-(propan-2-yl)benzoate (CAS 1178649-39-2)
- 1-(1-Methyl-1H-pyrazol-4-yl)pyrrolidin-3-amine (CAS 1153295-09-0)
- 1,3-Dimethyl-6-nitro-3,4-dihydroquinazolin-2(1H)-one (CAS 233775-52-5)
- 2-Bromo-5-methoxy-3-methylpyridine (CAS 1256809-85-4)
- 4-hydroxy-3-(prop-2-en-1-yl)benzaldehyde 41052-88-4 SP728 (CAS 41052-88-4)
- Vitamin K1-d7 (CAS 1233937-39-7)
- [(2,2,2-trifluoroethyl)sulfanyl]methanimidamide, trifluoromethanesulfonic acid (CAS 1384428-54-9)
- 2-((Tetrahydro-2H-pyran-4-yl)oxy)pyridin-3-amine (CAS 1211758-68-7)
- Tirzepatide Impurity 9 (CAS CATO-C4X-32409)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com