2,2',2'',2'''-(Butane-2,3-diylbis(azanetriyl))tetraacetic acid CAS 2458-58-4
| CAS No. | 2458-58-4 |
| Molecular Formula | C12H20N2O8 |
| Molecular Weight | 320.30 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
2,2',2'',2'''-(Butane-2,3-diylbis(azanetriyl))tetraacetic acid (CAS 2458-58-4), molecular formula C12H20N2O8 and molecular weight 320.30 g/mol, is a CATO reference standard with documented purity and traceability.
Structurally, 2,2',2'',2'''-(Butane-2,3-diylbis(azanetriyl))tetraacetic acid (C12H20N2O8) contains an amino-acid-derived structure, an amide group, a hydroxyl group, an ether linkage. The molecule exhibits a degree of unsaturation (DBE) of 4.0, corresponding to approximately 4 ring(s) or double-bond equivalent(s). With a molecular weight of 320.30 g/mol, it falls into the moderately-high-molecular-weight range. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C12H20N2O8 |
| Molecular Weight | 320.30 g/mol |
| Appearance | Off-white to pale yellow crystalline powder |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 4.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1957 |
| Nitrogen Atoms | 2 |
Related Butane Standards
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Recommended Standards
- 2-((4-Fluorophenyl)thio)-N-(5-(isoxazol-5-yl)-1,3,4-oxadiazol-2-yl)acetamide (CAS 952874-06-5)
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- 1-[2-(1,3-Dioxo-1,3-dihydro-2H-isoindol-2-yl)ethyl]-1H-indole-2,3-dione (CAS 303065-17-0)
- 2,5-Dioxopyrrolidin-1-yl 2-(((benzyloxy)carbonyl)amino)propanoate (CAS 73488-77-4)
- 5-Heptyl-1,3,4-thiadiazol-2-amine (CAS 75122-52-0)
- Tert-butyl 5-(4-formylphenyl)-3,3a,4,6a-tetrahydrocyclopenta[c]pyrrole-2(1H)-carboxylate (CAS 2489636-20-4)
- 3-bromoimidazo[1,2-a]pyridin-7-amine (CAS 1092352-46-9)
- 7-Aminoisoquinoline-1,3(2H,4H)-dione (CAS 882043-57-4)
- 2-(4-Propyl-1H-pyrazol-1-yl)acetic acid (CAS 1707571-05-8)
- 2-(1H-Tetrazol-1-yl)ethan-1-amine (CAS 926649-00-5)
- 2-cyclopropyl-2-methoxyethan-1-ol (CAS 1783648-29-2)
- Mivacurium chloride Impurity 78 (CAS CATO-C4X-137578)
- Axitinib Impurity 72 (CAS CATO-C4X-107172)
- Tirzepatide Impurity 19 X TFA Salt (CAS CATO-C4X-324019)
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