Clevidipine Butyrate impurity 20 CAS 2458150-60-0
| CAS No. | 2458150-60-0 |
| Molecular Formula | C21H23Cl2NO6 |
| Molecular Weight | 456.32 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
As a certified reference material (CRM), Clevidipine Butyrate impurity 20 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
As a process- or degradation-related impurity, Clevidipine Butyrate impurity 20 (CAS 2458150-60-0, C21H23Cl2NO6) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
Structurally, Clevidipine Butyrate impurity 20 (C21H23Cl2NO6) contains a flavonoid core, an amide group, a hydroxyl group, an ether linkage, chlorine substitution. The molecule exhibits a degree of unsaturation (DBE) of 10.0, corresponding to approximately 10 ring(s) or double-bond equivalent(s). With a molecular weight of 456.32 g/mol, it falls into the moderately-high-molecular-weight range. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
Physical & Chemical Properties
| Molecular Formula | C21H23Cl2NO6 |
| Molecular Weight | 456.32 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at room temperature, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 10.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2000 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 1 |
Related Clevidipine Standards
- Clevidipine Butyrate (CAS 167221-71-8)
- Clevidipine butyrate Impurity 4 (CAS 188649-48-1)
- Clevidipine-d5 (CAS 1346602-00-3)
- Clevidipine-d7 (CAS CATO-C4X-101523)
- Clevidipine butyrate Impurity 6 (CAS 175688-79-6)
- Clevidipine butyrate Impurity 9 (CAS CATO-C4X-10159)
- Clevidipine Impurity 33 (CAS CATO-C4X-101533)
- Clevidipine Impurity 39 (CAS CATO-C4X-101539)
Recommended Standards
- Fmoc-3,4-dichloro-D-Phe-OH (CAS 177966-58-4)
- Fmoc-2,4-dichloro-D-phenylalanine (CAS 352351-61-2)
- 2-Bromo-N-[(2,5-dimethoxyphenyl)methyl]-N-(2-phenoxyphenyl)-acetamide (CAS 1104493-09-5)
- Fmoc-(S)-3-Amino-3-(2,4-dichlorophenyl)-propionic acid (CAS 501015-34-5)
- Brexpiprazole Impurity 172 (CAS CATO-C4X-1131172)
- Levosimendan Impurity 55 (CAS CATO-C4X-130855)
- Brexpiprazole Impurity 110 (CAS 433303-94-7)
- (4-Methyl-3-nitrophenyl)hydrazine (CAS 98547-96-7)
- 1-(3-Phenylureido)propan-2-yl phenylcarbamate (CAS 132104-26-8)
- N-((1H-benzo[d][1,2,3]triazol-1-yl)methyl)isobutyramide (CAS 143949-77-3)
- n,1-Diisopropyl-1h-pyrazolo[3,4-b]pyridin-5-amine (CAS 1042561-99-8)
- 3-ethyl-1-[2-(1H-pyrazol-1-yl)ethyl]piperazine (CAS 1334146-93-8)
- (E)-1-(2-chloro-4-(4-chlorophenoxy)phenyl)-3-(dimethylamino)prop-2-en-1-one (CAS 477851-90-4)
- Liraglutide(10-22)TFA Salt (CAS CATO-C4X-199211)
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