2-[2-(trifluoromethyl)-1h-1,3-benzodiazol-1-yl]acetohydrazide CAS 246163-29-1
| CAS No. | 246163-29-1 |
| Molecular Formula | C10H9F3N4O |
| Molecular Weight | 258.20 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
2-[2-(trifluoromethyl)-1h-1,3-benzodiazol-1-yl]acetohydrazide (CAS 246163-29-1) is a high-purity analytical reference standard with the molecular formula C10H9F3N4O and a molecular weight of 258.20 g/mol.
The molecular framework of 2-[2-(trifluoromethyl)-1h-1,3-benzodiazol-1-yl]acetohydrazide (C10H9F3N4O) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
As a certified reference material (CRM), 2-[2-(trifluoromethyl)-1h-1,3-benzodiazol-1-yl]acetohydrazide meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C10H9F3N4O |
| Molecular Weight | 258.20 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 7.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 4 |
Related trifluoromethyl Standards
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- Ethyl 2-(trifluoromethyl)imidazo[1,2-a]pyridine-3-carboxylate (CAS 108438-46-6)
- 2-(6-(Trifluoromethyl)imidazo[1,2-a]pyridin-2-yl)acetohydrazide (CAS 1221792-29-5)
- Methyl 2-(6-(trifluoromethyl)imidazo[1,2-a]pyridin-2-yl)acetate (CAS 1221792-68-2)
- 2-{1-[5-(trifluoromethyl)pyridin-2-yl]-1H-1,2,3-triazol-4-yl}ethan-1-ol (CAS 1240526-47-9)
Recommended Standards
- 2-(4-Fluorophenyl)[1,3]oxazolo[5,4-b]pyridine-6-carboxylic acid (CAS 927801-37-4)
- 3-[2-(Trifluoromethyl)-1h-benzimidazol-1-yl]propanoic acid (CAS 526205-52-7)
- 2-(4-Cyanophenoxy)-N-(2,2,2-trifluoroethyl)acetamide (CAS 923238-36-2)
- 3-Bromo-N,N-dimethyladamantan-1-amine (CAS 944-10-5)
- N-{3-(Dimethylamino)-1-[(4-methoxyphenyl)sulfonyl]-1H-1,2,4-triazol-5-yl}-N,N-dimethylamine (CAS 478032-04-1)
- (2E,2'E)-4,4'-(naphthalene-1,5-diylbis(azanediyl))bis(4-oxobut-2-enoic acid) (CAS 293323-14-5)
- 1-(2-FLuorobenzyl)-1,2,3,6-tetrahydropyridine hydrochloride (CAS 73081-25-1)
- Magnesium potassium chloride (CAS 15681-05-7)
- 3-Amino-N-(3-bromo-4-methylphenyl)-6-(pyridin-4-yl)thieno[2,3-b]pyridine-2-carboxamide (CAS 626226-18-4)
- (S,E)-3-((((9H-Fluoren-9-yl)methoxy)carbonyl)amino)-6-phenylhex-5-enoic acid (CAS 1217460-65-5)
- 2-(1-Methyl-1H-pyrrol-2-yl)-2-oxo-N-(4-phenoxyphenyl)acetamide (CAS 477872-03-0)
- 2-(Difluoromethyl)thiazole (CAS 2149601-66-9)
- MSDC-0160, >98% (CAS 146062-49-9)
- Prolactin-Releasing Peptide (1-31) (rat) (CAS 215510-06-8)
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