1,1'-[(1S)-6,6'-Dimethoxy[1,1'-biphenyl]-2,2'-diyl]bis[1,1-dicyclohexylphosphine] CAS 246223-35-8

Description

Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including 1,1'-[(1S)-6,6'-Dimethoxy[1,1'-biphenyl]-2,2'-diyl]bis[1,1-dicyclohexylphosphine].

CATO supplies 1,1'-[(1S)-6,6'-Dimethoxy[1,1'-biphenyl]-2,2'-diyl]bis[1,1-dicyclohexylphosphine] (CAS 246223-35-8), a certified reference material (molecular formula C38H56O2P2, MW 606.80 g/mol) for analytical method development and quality control.

1,1'-[(1S)-6,6'-Dimethoxy[1,1'-biphenyl]-2,2'-diyl]bis[1,1-dicyclohexylphosphine] (C38H56O2P2) contains organophosphorus functionality, a carboxylic acid group, a hydroxyl group, an ether linkage, a polycyclic aromatic system. Its high carbon-to-hydrogen ratio confers good lipid solubility, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.

Physical & Chemical Properties

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