4-(Chloromethyl)-1,3-dioxolan-2-one CAS 2463-45-8
| CAS No. | 2463-45-8 |
| Molecular Formula | C4H5ClO3 |
| Molecular Weight | 136.53 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The molecular framework of 4-(Chloromethyl)-1,3-dioxolan-2-one (C4H5ClO3) is characterized by a carboxylic acid group, a hydroxyl group, an ether linkage, chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by the polarity and ionization state of its functional groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
CATO supplies 4-(Chloromethyl)-1,3-dioxolan-2-one (CAS 2463-45-8), a certified reference material (molecular formula C4H5ClO3, MW 136.53 g/mol) for analytical method development and quality control.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
CATO manufactures 4-(Chloromethyl)-1,3-dioxolan-2-one under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C4H5ClO3 |
| Molecular Weight | 136.53 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, ethanol, DMSO, water |
| Stability | Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 2.0 |
| CAS Registry Year (est.) | 1957 |
| Halogen Content | Cl-containing |
Related Chloromethyl Standards
- 4-Chloromethyl-[1,3]dioxane (CAS 1121-62-6)
- [3-(chloromethyl)oxetan-3-yl]methanol (CAS 4351-77-3)
- 2-(Chloromethyl)-1,3-dioxane (CAS 5695-72-7)
- 2-(Chloromethyl)-1,4-dioxane (CAS 21048-16-8)
- 2-(Chloromethyl)-2-methyl-1,3-dioxolane (CAS 4469-49-2)
- 5-(Chloromethyl)-1,3-dioxane (CAS 61728-98-1)
- Chloromethyl Isobutyrate (CAS 61644-18-6)
- Chloromethyl Butyrate (CAS 33657-49-7)
Recommended Standards
- 3-Chloro-2-oxobutanoic acid (CAS 142521-41-3)
- Chloroacetic Acetic AnhydrideDISCONTINUED (CAS 4015-58-1)
- oxetan-3-yl carbonochloridate (CAS 1202640-00-3)
- Ethyl chlorooxoacetate (CAS 4755-77-5)
- 5-Methylpyrimidine-2-carboxamide (CAS 87362-33-2)
- 7-Chloro-2-methyl-1H-pyrrolo[3,2-b]pyridine (CAS 1260384-60-8)
- Fmoc-Thr(tBu)-OPfp (CAS 117088-31-0)
- 4,5-Bis(2,3-difluorophenyl)-2-fluoropyridine (CAS 1261482-76-1)
- 1-(1H-benzo[d]imidazol-2-yl)-3-methyl-4-phenyl-1H-pyrazol-5-amine (CAS 890645-46-2)
- 6-Chloro-N4-(3,4-dimethoxyphenyl)pyrimidine-2,4-diamine (CAS 339016-02-3)
- 8-Hydroxyquinoline-5-sulfonic acid hydrate (CAS 283158-18-9)
- Ethyl 5-nitro-nicotinate (CAS 1462-89-1)
- 5-Methyloctan-4-ol (CAS 59734-23-5)
- Anti-TF Antigen Peptide P30-1 trifluoroacetate salt (CAS 573664-50-3)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com