P-hydroxyphenyl Glyoxal monohydrate CAS 24645-80-5
| CAS No. | 24645-80-5 |
| Molecular Formula | C8H6O3 |
| Molecular Weight | N/A |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including P-hydroxyphenyl Glyoxal monohydrate.
P-hydroxyphenyl Glyoxal monohydrate (CAS 24645-80-5) is a high-purity analytical reference standard with the molecular formula C8H6O3H2O and a molecular weight of 168.15 g/mol.
The molecular framework of P-hydroxyphenyl Glyoxal monohydrate (C8H6O3H2O) is characterized by a carboxylic acid group, a hydroxyl group, an ether linkage, an aromatic ring system. In reversed-phase chromatography, its retention is governed primarily by the polarity and ionization state of its functional groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C8H6O3 H2O |
| Molecular Weight | 168.15 g/mol |
| Appearance | Off-white to pale yellow crystalline powder |
| Purity | >80% |
| Storage | Store at 2-8°C, keep sealed and dry |
| Solubility (reference) | Soluble in methanol, ethanol, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 5.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1964 |
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