3-(2-Chlorophenyl)prop-2-ynoic acid CAS 24654-08-8
| CAS No. | 24654-08-8 |
| Molecular Formula | C9H5ClO2 |
| Molecular Weight | 180.59 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
3-(2-Chlorophenyl)prop-2-ynoic acid (CAS 24654-08-8) is a high-purity analytical reference standard with the molecular formula C9H5ClO2 and a molecular weight of 180.59 g/mol.
Based on its molecular formula C9H5ClO2, 3-(2-Chlorophenyl)prop-2-ynoic acid contains a carboxylic acid group, a hydroxyl group, an ether linkage, chlorine substitution, an aromatic ring system; these features give the compound characteristic absorption bands in UV spectroscopy. The molecular weight of 180.59 g/mol is directly relevant to the identification of the molecular ion in mass spectrometry. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
As a certified reference material (CRM), 3-(2-Chlorophenyl)prop-2-ynoic acid meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C9H5ClO2 |
| Molecular Weight | 180.59 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 7.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1964 |
| Halogen Content | Cl-containing |
Related Chlorophenyl Standards
- 3-(4-Chlorophenyl)-1,2,5-oxadiazole (CAS 10349-08-3)
- 3-(4-Chlorophenyl)-1,2,4-oxadiazole (CAS 10550-15-9)
- 5-(4-Chlorophenyl)-1H-tetrazole (CAS 16687-61-9)
- 1-(4-Chlorophenyl)-1h-1,2,3,4-tetrazole (CAS 25108-32-1)
- 2-(3-Chlorophenyl)-1,3,4-oxadiazole (CAS 5378-33-6)
- 2-(4-Chlorophenyl)-1,3,4-oxadiazole (CAS 23289-10-3)
- 3-(3-Chlorophenyl)prop-2-ynoic acid (CAS 7396-28-3)
- 3-(4-Chlorophenyl)propiolic acid (CAS 3240-10-6)
Recommended Standards
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- N-Methyl-5-(2-thienyl)isoxazole-3-carboxamide (CAS 1019656-20-2)
- tert-butyl N-({1-[3-(hydroxymethyl)phenyl]-1H-1,2,3-triazol-4-yl}methyl)carbamate (CAS 2059948-51-3)
- 2-methanesulfonylacetohydrazide (CAS 82831-72-9)
- (S)-3-(1-Carboxy-3-methylbutyl)-1-mesityl-1H-imidazol-3-ium hexafluorophosphate(V) (CAS 1788856-37-0)
- 1-(2-Iodobenzyl)pyrrolidine (CAS 138154-61-7)
- 1-Aminoperylene (CAS 35337-21-4)
- Semaglutide impurity 236 (CAS CATO-C4X-2226236)
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