3-(4-(Trifluoromethyl)phenyl)acrylonitrile CAS 24654-53-3
| CAS No. | 24654-53-3 |
| Molecular Formula | C10H6F3N |
| Molecular Weight | 197.16 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
3-(4-(Trifluoromethyl)phenyl)acrylonitrile (CAS 24654-53-3) is a high-purity analytical reference standard with the molecular formula C10H6F3N and a molecular weight of 197.16 g/mol.
The molecular framework of 3-(4-(Trifluoromethyl)phenyl)acrylonitrile (C10H6F3N) is characterized by a nitrogen-containing heterocyclic scaffold, a nitrile group, fluorine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
CATO manufactures 3-(4-(Trifluoromethyl)phenyl)acrylonitrile under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C10H6F3N |
| Molecular Weight | 197.16 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 7.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1964 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 1 |
Related Trifluoromethyl Standards
- 6-(Trifluoromethyl)piperidine-3-carboxylic acid (CAS 1155103-14-2)
- Methyl 4-(trifluoromethyl)pyrrolidine-3-carboxylate (CAS 1190043-09-4)
- 7-(Trifluoromethyl)isoquinoline (CAS 1194375-56-8)
- 6-(Trifluoromethyl)isoquinoline (CAS 1194375-62-6)
- 4-(Trifluoromethyl)isoquinoline (CAS 120568-08-3)
- 8-(trifluoromethyl)isoquinoline (CAS 120568-10-7)
- 2-(Trifluoromethyl)piperidine-3-carboxylic acid (CAS 1240528-93-1)
- 2-(5-(Trifluoromethyl)pyrrolidin-2-yl)acetic acid (CAS 1258640-31-1)
Recommended Standards
- 3-(3-(Trifluoromethyl)phenyl)acrylonitrile (CAS 58177-64-3)
- 3-(Trifluoromethyl)quinoline (CAS 25199-76-2)
- 2-Amino-2-(trifluoromethyl)hex-5-enoic acid (CAS 887267-88-1)
- 3-[1-(Trifluoromethyl)vinyl]benzonitrile (CAS 893739-06-5)
- Ethyl 1H-benzo[d][1,2,3]triazole-1-carboxylate (CAS 830-67-1)
- trans-4-Ethoxy-4'-(4-propylcyclohexyl)-1,1'-biphenyl (CAS 118106-62-0)
- (S)-3-Aminopiperidin-2-One Hydrochloride (CAS 42538-31-8)
- Niraparib Impurity 17 HCl (CAS CATO-C4X-232917)
- 2-Cyclopropylpropan-1-amine 4-methylbenzenesulfonate (CAS 172947-14-7)
- 6-Bromo-8-fluoro-2-methylimidazo[1,2-a]pyridine (CAS 1446334-75-3)
- 4-(2,5-Dichlorophenyl)-2-methylthiomorpholine-3,5-dione (CAS 344265-96-9)
- 8-Methoxy-2-phenylquinoline-4-carboxylic Acid (CAS 489-75-8)
- (Propane-2,2-diylbis(2-hydroxybenzene-5,3,1-triyl))tetramethanol (CAS 3957-22-0)
- Peptide Impurity 13 (CAS CATO-CPTD788813)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
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