5-Chloro-1H-indol-3-amine hydrochloride(1:1) CAS 2470435-57-3
| CAS No. | 2470435-57-3 |
| Molecular Formula | C8H7ClN2 |
| Molecular Weight | N/A |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Compared with other compounds in its class, the molecular weight of 203.07 g/mol gives 5-Chloro-1H-indol-3-amine hydrochloride(1:1) distinctive chromatographic separation conditions and mass-spectrometry parameter settings.
5-Chloro-1H-indol-3-amine hydrochloride(1:1) (CAS 2470435-57-3), molecular formula C8H7ClN2HCl and molecular weight 203.07 g/mol, is a CATO reference standard with documented purity and traceability.
The molecular framework of 5-Chloro-1H-indol-3-amine hydrochloride(1:1) (C8H7ClN2HCl) is characterized by a nitrogen-containing heterocyclic scaffold, a nitrile group, chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C8H7ClN2 HCl |
| Molecular Weight | 203.07 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 5.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2000 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 2 |
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- 1-(3,4-Dimethoxyphenyl)-4-oxocyclohexanecarboxylic Acid (CAS 887978-64-5)
- tert-Butyl (2-chloro-5-methylthiazol-4-yl)carbamate (CAS 1823913-82-1)
- 4-(diethylamino)-2-hydroxybenzoic acid (CAS 23050-90-0)
- 1-(Bicyclo[1.1.0]butan-1-yl)ethanone (CAS 24464-70-8)
- Allo-Thr5-Tirzepatide (CAS CATO-CPTD788934)
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