2’-Chloro-4’-(trifluoromethyl)acetanilide CAS 247170-19-0
| CAS No. | 247170-19-0 |
| Molecular Formula | C9H7ClF3NO |
| Molecular Weight | 237.61 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including 2’-Chloro-4’-(trifluoromethyl)acetanilide.
CATO supplies 2’-Chloro-4’-(trifluoromethyl)acetanilide (CAS 247170-19-0), a certified reference material (molecular formula C9H7ClF3NO, MW 237.61 g/mol) for analytical method development and quality control.
The molecular framework of 2’-Chloro-4’-(trifluoromethyl)acetanilide (C9H7ClF3NO) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine/chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C9H7ClF3NO |
| Molecular Weight | 237.61 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 5.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | F/Cl-containing |
| Nitrogen Atoms | 1 |
Related Chloro Standards
- 2-Chloro-N-cyclopropyl-5-(trifluoromethyl)pyrimidin-4-amine (CAS 1050602-61-3)
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Recommended Standards
- 1-(4-Amino-3-chloro-5-(trifluoromethyl)phenyl)ethanone (CAS 97760-76-4)
- 2-Chloro-N-(2-(trifluoromethyl)phenyl)acetamide (CAS 3792-04-9)
- 1-[3-chloro-5-(trifluoromethyl)pyridin-2-yl]propan-2-one (CAS 400077-39-6)
- 2-Chloro-n-(2,3,4-trifluorophenyl)propanamide (CAS 731011-90-8)
- 1-[(tert-Butoxy)carbonyl]-4-methoxy-2,3-dihydro-1H-indole-2-carboxylic acid (CAS 899825-45-7)
- 2-(3-(Trifluoromethyl)phenyl)benzo[d]thiazole (CAS 133389-19-2)
- N-1-Fmoc-1,2-diaminoethane · HCl (CAS 391624-46-7)
- 3,5-diethyl-1-phenyl-1H-pyrazole (CAS 848153-41-3)
- 4-(1,2,3,6-Tetrahydropyridin-4-yl)phenol (CAS 90684-15-4)
- N-[(4-formylphenyl)methyl]butanamide (CAS 1354638-37-1)
- n-Benzyl-2-(pyrimidin-2-ylamino)acetamide (CAS 1181876-15-2)
- DL-Phenylalaninol (CAS 16088-07-6)
- 5-Bromo-4-chloro-2-fluorobenzonitrile (CAS 1824089-00-0)
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