1-Bromo-4-butoxy-2,3-difluorobenzene CAS 247176-22-3
| CAS No. | 247176-22-3 |
| Molecular Formula | C10H11BrF2O |
| Molecular Weight | 265.09 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
1-Bromo-4-butoxy-2,3-difluorobenzene (CAS 247176-22-3), molecular formula C10H11BrF2O and molecular weight 265.09 g/mol, is a CATO reference standard with documented purity and traceability.
The molecular framework of 1-Bromo-4-butoxy-2,3-difluorobenzene (C10H11BrF2O) is characterized by a hydroxyl group, an ether linkage, fluorine/bromine substitution, an aromatic ring system. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.
As a certified reference material (CRM), 1-Bromo-4-butoxy-2,3-difluorobenzene meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C10H11BrF2O |
| Molecular Weight | 265.09 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at room temperature, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure |
| Degree of Unsaturation (DBE) | 4.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | F/Br-containing |
Related Bromo Standards
- 4-bromo-1-(difluoromethoxy)-2-isopropylbenzene (CAS 1062616-03-8)
- 1-Bromo-4-butoxy-2,5-difluorobenzene (CAS 1235548-06-7)
- 1-Bromo-2-butoxy-3,5-difluorobenzene (CAS 1309932-84-0)
- 5-Bromo-2-butoxy-1,3-difluorobenzene (CAS 1309932-85-1)
- 5-Bromo-1,3-difluoro-2-(2-methylpropoxy)benzene (CAS 1309933-03-6)
- 1-Bromo-3,5-difluoro-2-isobutoxybenzene (CAS 1309933-15-0)
- 1-Bromo-4,5-difluoro-2-isobutoxybenzene (CAS 1309933-65-0)
- 1-Bromo-3-butoxy-2,4-difluorobenzene (CAS 1881290-22-7)
Recommended Standards
- 1-Bromo-1,1,2,2-tetrafluorooctane (CAS 231630-92-5)
- 2-(2,4-Dichlorophenoxy)nicotinonitrile (CAS 289662-03-9)
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- 2-(2,4-dichlorophenoxy)pyridine-4-carbonitrile (CAS 81249-46-9)
- N-Acetyl-N-(9H-fluoren-2-yl)acetamide (CAS 642-65-9)
- 2-(3-(Benzyl(ethyl)amino)pyrrolidin-1-yl)ethanol (CAS 1353954-61-6)
- [(1-ISopropyl-1h-indol-4-yl)oxy]acetic acid (CAS 2108810-86-0)
- 1-Phenethylazetidin-3-ol (CAS 1341952-55-3)
- 4-(2H-1,3-benzodioxol-5-yl)-3-cyclopropyl-1H-pyrazol-5-amine (CAS 1312617-86-9)
- (E)-1-(4-Bromo-2-hydroxyphenyl)-3-(diethylamino)prop-2-en-1-one (CAS 1159978-69-4)
- 1-(Benzo[d][1,3]dioxol-5-ylmethyl)-1H-tetrazole-5-thiol (CAS 890095-78-0)
- 3-[5-(7-hydroxyhept-1-ynyl)-1-oxo-isoindolin-2-yl]piperidine-2,6-dione (CAS 2619512-20-6)
- 2,2'-((Allyloxy)methylene)bis(1,3-dimethylbenzene) (CAS 130525-17-6)
- SAMS Peptide (CAS 125911-68-4)
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