(2R)-2-(Benzyloxy)-1-(2,4-difluorophenyl)-propan-1-one CAS 247196-88-9

Purity 97%+In StockPharmaceutical Standards
CAS No.247196-88-9
Molecular FormulaC16H14F2O2
Molecular Weight276.28 g/mol
CategoryPharmaceutical Standards / API Standards
AvailabilityIn Stock

Chemical Structure

(2R)-2-(Benzyloxy)-1-(2,4-difluorophenyl)-propan-1-one CAS 247196-88-9 chemical structure

Description

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

(2R)-2-(Benzyloxy)-1-(2,4-difluorophenyl)-propan-1-one (CAS 247196-88-9) is a high-purity analytical reference standard with the molecular formula C16H14F2O2 and a molecular weight of 276.28 g/mol.

Owing to a carboxylic acid group, a hydroxyl group, an ether linkage, fluorine substitution, a polycyclic aromatic system, (2R)-2-(Benzyloxy)-1-(2,4-difluorophenyl)-propan-1-one is typically pale yellow to yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 276.28 g/mol — guide the selection of appropriate sample preparation and analytical techniques. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.

As a certified reference material (CRM), (2R)-2-(Benzyloxy)-1-(2,4-difluorophenyl)-propan-1-one meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.

Physical & Chemical Properties

Molecular FormulaC16H14F2O2
Molecular Weight276.28 g/mol
AppearancePale yellow to yellow crystalline powder. (slight halide-like odor, low volatility)
Purity97%+
StorageStore at 2-8°C, protect from light, keep tightly closed to prevent evaporation
Solubility (reference)Soluble in chloroform, dichloromethane, ethyl acetate, DMSO
StabilityMay oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions
Degree of Unsaturation (DBE)9.0
UV AbsorptionUV-absorbing
Structural FeaturesAromatic ring present
CAS Registry Year (est.)2025
Halogen ContentF-containing

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